Keywords
Blood component transfusion
Prehospital care
Advanced trauma life support care
Shock hemorrhagic
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Abstract
Objective: Identify the use of packed red blood cells in pre-hospital care (PHC) as a strategy to reduce morbidity and mortality in patients suffering from severe trauma with class III and IV hemorrhagic shock. Methods: Integrative literature review in the Latin American and Caribbean Literature in Health Sciences databases, in the National Library of Medicine and in the Scientific Electronic Library Online, carried out between April 2022 and May 2023, using the 6 steps of the methodology in an integrative review, using evidence from the last ten years as a temporal cut-off. Results: The sample consisted of 26 articles, which described the use of packed red blood cells in pre-hospitall and andair care for trauma and poly trauma patients with class III hemorrhagic shock, and a reduction in the morbidity and mortality rate of these patients was noted patients in the first 24 hours after trauma. Final considerations: Despite the debates regarding the benefits and risks to the patient, it is evident in the literature that the practice of transfusing packed red blood cells in PHC has been astrategy adopted in several countries, which has brought benefits, suchas reducing the rate of morbidity and mortality in the first 24 hours of trauma and polytrauma victims.
References
ACS. AMERICAN COLLEGE OF SURGEONS. Advanced Trauma Life Support. Student Course Manual, 2018; 18.
BICHOT A, et al. Use of prehospital transfusion by French emergency medical services: A national survey. Transfusion, 2023; 63(3): 241-248.
BJERKVIF CK, et al. Prehospital Whole Blood Transfusion Programs in Norway. Transfus Med Hemother, 2021; 48(6): 324-331.
BOTELHO LLR, et al. O método da revisão integrativa nos estudos organizacionais. Gestão e Sociedade, 2011; 5(11): 121-136.
BRASIL. Corpo de Bombeiros. Comando Operacional. Grupamento de Atendimento de Emergência Pré- Hospitalar. Manual de Atendimento Pré-Hospitalar do Corpo de Bombeiros Militar do Distrito Federal/Grupamento de Atendimento de Emergência Pré-Hospitalar [Corpo de Bombeiros Militar do Distrito Federal: CBMDF, 2022; 2.
BRASIL. MINISTÉRIO DA SAÚDE. Secretaria de Atenção à Saúde. Departamento de Atenção Especializada e Temática. Guia para uso de hemocomponentes / Ministério da Saúde, Secretaria de Atenção à Saúde, Departamento de Atenção Especializada e Temática. Brasília: Ministério da Saúde, 2015; 2(1).
BRASIL. PREFEITURA DE BRAGANÇA PAULISTA. Transfusão de sangue no SAMU: Projeto pioneiro na América Latina completa um ano em Bragança Paulista. São Paulo, 2021.
BRAVERMAN MA, et al. Pre hospital whole blood reduces early mortality in patients with hemorrhagic shock. Transfusion, 2021; 61(1): 15-21.
CASELLI-BELÉM, R. Suporte de vida para times de trauma [livro eletrônico ] : manual prático, 2025.
CERTAIN L, et al. First immediate transfusion at a prehospital environment in Latin America: A case report. Hematol Transfus Cell Ther, 2021; 26: 2531-1379.
CERTAIN L, et al. Implementation of a pre-hospital transfusion service in Latin America: the pioneering experience of a Brazilian centre. ISBT Sci Ser, 2021.
CROCHEMORE T, et al. Thromboelastometry profile in critically ill patients: A single-center, retrospective, observational study. PLoS One, 2018; 13(2): 192965.
CROMBIEN, et al. Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving pre hospital care (RePHILL): a multi centre, open-label, randomised, controlled, phase 3 trial. Lancet Haematol, 2022; 9(4): 250-261.
DUDARYK R, et al. Pro-Con Debate: Prehospital Blood Transfusion-Should It Be Adopted for Civilian Trauma? Anesth Analg, 2022; 134(4): 678-682.
GARCIA-GARCIA LR, et al. Primera transfusión extrahospitalaria en Aragón a paciente COVID-19. Hosp. domic, 2021; 5(4): 217-224.
HAJJAR L, et al. Medicina de emergência: abordagem prática. Santana de Parnaíba, SP: Manole, 2024; 18.
HERLON SM, et al. Emergências clínicas: abordagem prática. Barueri, SP: Manole, 2015; 10.
JOST D, et al. Frenchly ophilized plasma versus normal saline for post-traumatic coagulopathy prevention and correction: PREHO-PLYO protocol for a multicenter randomized controlled clinical trial. Trials, 2020; 21(1): 106.
LYON RM, et al. Pre- hospital transfusion of packed red blood cells in 147 patients from a UK helicopter emergency medical service. Scand J Trauma Resusc Emerg Med, 2017; 25: 12.
MIX FM, et al. Prehospital Blood Product Administration Opportunities in Ground Transport ALS EMS - A Descriptive Study. Prehosp Disaster Med, 2018; 33(3): 230-236.
MOORE HB, et al. Plasma-first resuscitation to treat haemorrhagic shock during emergency ground transportation in an urban area: a randomised trial. Lancet, 2018; 392(10144): 283-291.
NAEMT. NATIONAL ASSOCIATION OF EMERGENCY MEDICAL TECHNICIANS. PHTLS-Prehospital Trauma Life Support. Jones & Bartlett Learning, 2022; 10.
NAEMT.NATIONAL ASSOCIATION OF EMERGENCY MEDICAL TECHNICIANS. PHTLS- Pre hospital Trauma Life Support. Jones & Bartlett Learning, 2020; 9.
PARKERME, et al. Prehospital transfusion for gastrointestinal bleeding. Air Med J , 2017; 36(6): 315–9.
REHNM, et al. Effect of Prehospital Red Blood Cell Transfusionon Mortality and Time of Deathin Civilian Trauma Patients. Shock, 2019; 51(3): 284-288.
REISDJC; et al. Análise da distribuição de hemocomponentes na hemorrede do distrito federal. Arq. ciências saúde, 2017; 21(2): 93-98.
RIJNHOUTTWH, et al. Is prehospital blood transfusion effective and safe in haemorrhagic trauma patients? A systematic review and meta-analysis. Injury, 2019; 50(5): 1017-1027.
ROEHLA e GROTTKEO. Prehospital administration of blood and plasma products. Curr Opin Anaesthesiol, 2021; 34(4): 507-513.
ROSSAINT R, et al. The European guideline on management of major bleeding and coagulopathy following trauma:. Crit Care, 2023; 27(6): 80.
SAYRE MR, et al. Providing whole blood for an urban paramedical ambulance system.Transfusion, 2022; 62(1): 82-86.
SMITHIM, et al. Prehospital Blood Product Resuscitation for Trauma: A Systematic Review. Shock, 2016; 46(1): 3-16.
THIESKC,et al. Pre-hospital blood transfusion-an ESA survey of European practice. Scand J Trauma Resusc Emerg Med, 2020; 28(1): 79.
THOMPSOM P e STRANDENES G. The History of Fluid Resuscitation for Bleeding. Damage Control Resuscitation, 2019; 6: 3–29.
TUCKER H, et al. Association of red blood cells and plasma transfusion versus red blood cell transfusion only with survival for treatment of major traumatic hemorrhage in prehospital setting in England: a multicenter study. Crit Care, 2023; 27(1): 25.
VOLLER J, et al. Joint Trauma System Clinical Practice Guideline (JTS CPG): Pre hospital Blood Transfusion. J Spec Oper Med, 2021; 21(4): 11-21.
YAZER MH, et al. Toward a more complete understanding of who will benefit from prehospital transfusion. Transfusion, 2022; 62(8): 1671-1679.
YLIHARJU H, et al. Initial experiences of prehospital blood product transfusions between 2016 and 2020 in Päijät-Häme hospital district, Finland. Scand J Trauma Resusc Emerg Med, 2022; 30(1): 39.