Keywords
Caries
Integrative Review
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Abstract
Objective: To analyze the most recent scientific evidence regarding the use of Nanosilver fluoride (NSF) in Dentistry. Methods: A search was conducted in the PubMed database in April 2025 using a strategy built with descriptors related to NSF and Boolean operators. Two independent authors selected the articles after reading the titles and abstracts according to the following inclusion criteria: full-text articles, no methodology restrictions, published in the last 10 years, and addressing NSF in Dentistry. Results: The initial search yielded 56 articles, of which 25 were included. The oldest study was published in 2017, and the most recent in 2024. Among the included articles, the most frequent study designs were randomized clinical trials (n=11) and laboratory studies (n=11). The main themes of the analyzed studies were to evaluate the efficacy (n=7) and antimicrobial capacity of NSF (n=7). Final Considerations: The evidence on the use of NSF focuses on its cariostatic and antibacterial characteristics, mainly against Streptococcus mutans. It is suggested that well-designed clinical studies be conducted to investigate the topic of tooth pigmentation after the use of NSF.
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