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Semaglutide (Ozempic®) and non-prescription aesthetic use: risks and future consequences
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Keywords

Semaglutide
Ozempic
Diabetes Mellitus
Obesity
Biomedicine

How to Cite

Semaglutide (Ozempic®) and non-prescription aesthetic use: risks and future consequences. (2025). Electronic Journal Collection Health, 25(8), e21141. https://doi.org/10.25248/reas.e21141.2025

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Abstract

Objective: The main objective of this study is to analyze the indiscriminate use of Semaglutide and the impacts that this practice may generate in the future. With the increasing use of this medication for non-prescription purposes, especially for weight loss, it is essential to understand the clinical, social and economic consequences of this trend. Literature review: This study was a narrative review of the off-label use of semaglutide (Ozempic®) for aesthetic purposes, highlighting its clinical and social risks. Although approved for the treatment of type 2 diabetes, its popularization on social media and self-medication have led to relevant adverse events, such as pancreatitis and gastrointestinal disorders. The review discussed the impact on the availability of the drug for diabetics and emphasized the importance of multidisciplinary management. Finally, it emphasized the essential role of biomedical professionals in promoting rational use, laboratory monitoring, and health education to reduce harm to public health. Final considerations: This review study analyzed the risks of indiscriminate use of semaglutide (Ozempic®), especially for aesthetic purposes and without medical advice. Despite its effectiveness in the treatment of type 2 diabetes and weight loss, uncontrolled use can cause serious adverse effects. The popularization of the drug on social media has favored self-medication. The work highlights the need for regulation, adequate information and more studies on the effects on non-diabetics.

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