Keywords
Pregnant women
Notification of diseases
Toxoplasmosis
Congenital toxoplasmosis
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Abstract
Objective: To describe the geographic distribution and epidemiological profile of confirmed cases of gestational toxoplasmosis (GT) and congenital toxoplasmosis (CT) in residents of the Legal Amazon (LA), from 2020 to 2024. Methods: This is a descriptive and cross-sectional epidemiological study, with a quantitative approach, carried out by collecting secondary data on confirmed cases of TG and TC in residents of the states that make up LA, Brazil, between 2020 and 2024. Confirmed cases, year of diagnosis, state of residence, evolution, diagnostic criteria, age group, schooling, gestational age and incidence rates were investigated. Results: During the period analyzed, 7998 cases of TG and 1781 cases of TC were confirmed in LA. Cases of the diseases have gradually increased over the years. In most LA states, the incidence rates of TG and TC were higher than the national rate. In addition, the pregnant women most affected by TG were between 20 and 39 years old, with completed high school, in the second trimester of pregnancy. Most of the cases were confirmed by laboratory tests and progressed to cure. Conclusion: The study revealed that TG and CT represent an important public health problem in LA.
References
AHMED M, et al. Toxoplasmosis in pregnancy. European Journal of Obstetrics & Gynecology and Reproductive Biology, 2020; 255: 44-50.
BIGNA JJ, et al. Global, regional, and country seroprevalence of Toxoplasma gondii in pregnant women: a systematic review, modelling and meta-analysis. Scientific Reports, 2020; 10(1): 12102.
BOLLANI L, et al. Congenital toxoplasmosis: the state of the art. Frontiers in Pediatrics, 2022; 10: 894573.
BRASIL. Ministério da Saúde. Secretaria de Vigilância em Saúde. Protocolo de notificação e investigação: toxoplasmose gestacional e congênita. Brasília: Ministério Da Saúde; 2018.
CAPOBIANGO JD, et al. Congenital toxoplasmosis in a reference center of Paraná, Southern Brazil. Brazilian Journal of Infectious Diseases, 2014; 18: 364-371.
CARVALHO AQS, et al. Epidemiologia da toxoplasmose na gravidez e pós-parto. Revista Enfermagem Atual In Derme, 2025; 99(supl. 1): e025076.
DE JESUS EB, et al. Perfil epidemiológico da toxoplasmose gestacional no Brasil de 2019 a 2023. Revista Eletrônica Acervo Científico, 2024; 47: e17709
EL BISSATI K, et al. Global initiative for congenital toxoplasmosis: an observational and international comparative clinical analysis. Emerging microbes & infections, 2018; 7(1): 1-14.
FALLAHI S, et al. An updated literature review on maternal-fetal and reproductive disorders of Toxoplasma gondii infection. Journal of gynecology obstetrics and human reproduction, 2018; 47(3): 133-140.
FELIX JE, et al. Avaliação do conhecimento das gestantes frente a toxoplasmose congênita. Brazilian Journal of Health Review, 2025; 8(1): e76653.
IHARA F, YAMAMOTO M. The role of IFN-γ-mediated host immune responses in monitoring and the elimination of Toxoplasma gondii infection. International Immunology, 2021; dxae001.
LEMOS ALF, SILVA JA. Desmatamento na Amazônia Legal: evolução, causas, monitoramento e possibilidades de mitigação através do Fundo Amazônia. Floresta e Ambiente, 2024; 18: 98-108.
LIMA AC, et al. DATASUS: o uso dos Sistemas de Informação na Saúde Pública. Refas-Revista Fatec Zona Sul, 2015; 1(3): 16-31.
MARINO ACA, et al. Toxoplasmose em gestantes no Acre: uma análise temporal do período compreendido entre 2019 a 2023. Brazilian Journal of Health Review, 2025; 8(2): e78632.
MCLEOD R, et al. Management of congenital toxoplasmosis. Current Pediatrics Reports, 2014; 2: 166-194.
POMARES C, MONTOYA JG. Laboratory diagnosis of congenital toxoplasmosis. Journal of clinical microbiology, 2016; 54(10): 2448-2454.
ROBERT-GANGNEUX F, DARDÉ ML. Epidemiology of and diagnostic strategies for toxoplasmosis. Clinical microbiology reviews, 2012; 25(2): 264-296.
ROBLES TVB, TEJEDOR JGO. Frecuencia de citomegalovirus, Toxoplasma gondii, Rubéola, Herpes virus en mujeres embarazadas y neonatos que acuden a la clínica Aguilar de la ciudad de Machala en el período 2020-2022. Polo del Conocimiento, 2014; 9(1): 1606-1619.
RODRIGUES NJL, et al. Atualizações e padrões da toxoplasmose humana e animal: revisão de literatura. Veterinária e Zootecnia, 2022; 29: 1-15.
ROSA VHJ, et al. Perfil epidemiológico da toxoplasmose gestacional no estado do Amazonas: Toxoplasmose gestacional no Amazonas. Brazilian Journal of Implantology and Health Sciences, 2024; 6(1): 981-991.
SANTOS HGM, et al. Perfil epidemiológico da toxoplasmose gestacional no Estado do Pará no período de 2019 a 2023. Revista Eletrônica Acervo Saúde, 2025; 25: e19188.
SILVA NP, et al. A utilização dos programas TABWIN e TABNET como ferramentas de apoio à disseminação das informações em saúde. 2009. Tese de Doutorado.
SOUZA VO, et al. Toxoplasmose adquirida na gestação e Toxoplasmose Congênita. BEPA. Boletim Epidemiológico Paulista, 2023; 20: 1-14.
STILLWAGGON E, et al. Maternal serologic screening to prevent congenital toxoplasmosis: a decision-analytic economic model. PLoS neglected tropical diseases, 2011; 5(9): e1333.
TEIMOURI A, et al. Role of Toxoplasma gondii IgG avidity testing in discriminating between acute and chronic toxoplasmosis in pregnancy. Journal of clinical microbiology, 2020; 58(9): 10.
TORGERSON PR, MASTROIACOVO P. The global burden of congenital toxoplasmosis: a systematic review. Bulletin of the World Health Organization, 2013; 91: 501-508.
VIANA ALA, et al. Sistema de saúde universal e território: desafios de uma política regional para a Amazônia Legal. Cadernos de Saúde Pública, 2007; 23: S117-S131.
VILLAR BBF, et al. Toxoplasmosis in pregnancy: a clinical, diagnostic, and epidemiological study in a referral hospital in Rio de Janeiro, Brazil. Brazilian Journal of Infectious Diseases, 2021; 24: 517-523.
WALLON M, et al. Congenital toxoplasma infection: monthly prenatal screening decreases transmission rate and improves clinical outcome at age 3 years. Clinical Infectious Diseases, 2013; 56(9): 1223-1231.
WALLON M, PEYRON F. Congenital toxoplasmosis: a plea for a neglected disease. Pathogens, 2018; 7(1): 25.
WEISS LM, DUBEY JP. Toxoplasmosis: A history of clinical observations. International journal for parasitology, 2009; 39(8): 895-901.