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Risk factors for Clostridioides difficile infection in Intensive Care Units
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Keywords

Clostridioides difficile
Fatores de risco
Unidades de terapia intensiva

How to Cite

Risk factors for Clostridioides difficile infection in Intensive Care Units. (2025). Electronic Journal Collection Health, 25(11), e21864. https://doi.org/10.25248/reas.e21864.2025

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Abstract

Objetivo: Identificar os fatores de risco para a infecção por Clostridioides difficile (ICD) em pacientes adultos internados em unidades de terapia intensiva. Métodos: Revisão integrativa da literatura, realizada por meio de busca na base de dados PubMed, incluindo artigos que avaliaram os fatores de risco para ICD em pacientes hospitalizados em unidades de terapia intensiva. As palavras-chave utilizadas foram “Clostridioides difficile”, “risk factors” e “intensive care units”. Resultados: A busca resultou em 74 artigos, dos quais 23 foram pré-selecionados para leitura e análise. Destes, 11 foram excluídos de acordo com o objetivo e os critérios de inclusão, sendo finalmente 12 artigos incluídos. Considerações finais: Os fatores de risco para ICD incluem o uso de antibióticos de amplo espectro, hospitalização prolongada, permanência em unidades de terapia intensiva, doença grave, idade avançada, terapia imunossupressora, nutrição enteral, inibidores da bomba de prótons, presença de comorbidades e distúrbios metabólicos. O conhecimento desses fatores é imprescindível para a prevenção e o adequado manejo terapêutico dos pacientes hospitalizados, sobretudo em unidades de terapia intensiva.

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