Keywords
Circadian cycle
Night workers
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Abstract
Objective: To evaluate the influence of circadian cycle inversion, caused by night work, on the erectile function of workers across different age groups, also considering possible physiological and occupational mechanisms involved. The study seeks to understand the physiological impacts related to erectile dysfunction in these individuals. Methods: A standardized questionnaire was applied to 303 male participants, of whom 3 were excluded due to incompatibility with the desired sample. The study included 78 workers exposed to night shifts and 222 not exposed. Participants were distributed into six age groups, and the collected data were statistically analyzed using the p-value to identify potential associations between night-work exposure and erectile function. Results: The analysis, considering all age groups and both categories, showed a p-value of 0.0789. This result indicated no statistical significance to reject the null hypothesis, demonstrating that there was no meaningful association between night work and erectile function. Conclusion: Circadian cycle inversion resulting from night work did not show a significant influence on erectile function among the evaluated participants. However, the findings reinforce the need for further research that includes hormonal variables, exposure duration, chronotype, and psychosocial factors as potential mediators of this relationship.
References
CHATTERJEE R, et al. Impact of occupational stress and sleep deprivation on male sexual function: interplay between neuroendocrine and psychosocial factors. Andrology, 2021; 9(5): 1387-1396.
CHEN L, YANG G. Recent advances in circadian rhythms in cardiovascular system. Front Pharmacol, 2015; 6: 71.
DARMON P. Le tribunal de l’impuissance. Paris: Seuil, 1979.
DENG N, et al. The relationship between shift work and men's health. Sex Med Rev, 2018; 6(3): 446-456.
DENG NF, et al. The effect of shift work on urogenital disease: a systematic review. Andrology and Infertility, 2018.
DEROUET H, et al. Erektile Funktionsstörungen. Epidemiologie, Physiologie, Atiologie, Diagnostik und Therapie. Nervenarzt, 2004; 75(6): 595-605.
DIAGNOSTIC CLASSIFICATION STEERING COMMITTEE. International Classification of Sleep Disorders. Diagnostic and Coding Manual. Rochester: American Sleep Disorders Association, 1990.
FELDMAN HA, et al. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol, 1994; 151(1): 54-61.
FERNANDES RMF. Distúrbios respiratórios do sono. Medicina (Ribeirão Preto), 2006; 39(2): 157-168.
JACKSON G. Erectile dysfunction and cardiovascular disease. Int J Clin Pract, 1999; 53(5): 363-368.
KRANE RJ, et al. Impotence. N Engl J Med, 1989; 321: 1648-1659.
MCMAHON CG. Erectile dysfunction. Intern Med J, 2014; 44(1): 18-26.
MOREIRA JUNIOR ED, et al. Epidemiologia da disfunção erétil Brasil: resultados da pesquisa nacional do Projeto Avaliar. Rev Bras Med, 2004; 61(9): 613-625.
PHÉ V, ROUPRÊT M. Erectile dysfunction and diabetes: a review of the current evidence-based medicine and a synthesis of the main available therapies. Diabetes Metab, 2012; 38(1): 1-13.
PHÉ V, et al. Etiologie et prise en charge de la dysfonction érectile chez le patient diabétique. Prog Urol, 2009; 19(6): 364-371.
SCHWARTZ JR, ROTH T. Shift work sleep disorder: burden of illness and approaches to management. Drugs, 2006; 66(18): 2357-2370.
SHAMLOUL R, GHANEM H. Erectile dysfunction. Lancet, 2013; 381(9861): 153-165.
TAKEDA N, et al. Circadian clock and cardiovascular disease. J Cardiol, 2011; 57: 249-256.
VETTER C, et al. Night shift work, genetic risk, and type 2 diabetes in the UK Biobank. Diabetes Care, 2018; 41(4): 762-769.
WALKER UA, et al. Erectile dysfunction in systemic sclerosis. Ann Rheum Dis, 2009; 68(7): 1083-1085.
WU FC, et al. Prevalence of erectile dysfunction and its associations in men: results from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3). Lancet, 2015; 385(9961): 333-341.
YAFI FA, et al. The link between testosterone deficiency and sleep disorders: implications for erectile dysfunction. Nat Rev Urol, 2017; 14(11): 671-685.
YUAN J, et al. Erectile dysfunction and cardiovascular risk: meta-analysis of prospective cohort studies. J Am Coll Cardiol, 2019; 73(21): 2709-2719.
ZHU Y, et al. Impact of circadian disruption on male reproductive health: from shift work to jet lag. Front Endocrinol, 2020; 11: 573634.
ZHUO L, et al. Shift work and risk of metabolic syndrome: a meta-analysis. Sleep Med Rev, 2019; 47: 18-26.