Abstract
Objective: To observe thyroid dysfunctions in patients with psoriasis. Methods: It is a clinical, transversal and prospective study. A sample of 40 patients with psoriasis and 20 controls were used. The study was approved by the Research Ethics Committee Results: There was a significant difference (p <0.0001) between the ages of patients in the psoriasis group when compared to the control group. Free T4 was altered in 38.3% and obtained an average of 1.6 ± 2.1. The control group presented a mean of 5.1 ± 3.7, with a significant difference (p <0.0004) between the groups. A significant difference was observed in the thyroid peroxidase antibody (anti-TPO) levels between the groups, (p<0.0015). Conclusion: Therefore, that there is a significant relationship between higher levels of anti-TPO in patients with psoriasis when compared to the control group. There was a significant increase in free T4 levels among patients in this group. No significant relationships were found between Psoriasis Area Severity Index (PASI) and thyroid changes.