Keywords
Patient Care Bundles
Checklist
Intensive Care Units
Hospital Costs
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Abstract
Objective: To evaluate the economic impact of bundle and checklist implementation in preventing CLABSI in ICUs. Methods: Systematic review without meta-analysis conducted according to PRISMA 2020 and PRISMA-P guidelines and registered in PROSPERO (CRD 42023470441). Nine databases were searched (2012-2022). Methodological quality was assessed using the Newcastle-Ottawa Scale. Results: Nine studies were included. Most were observational pre and post-intervention. Bundle and checklist implementation significantly reduced CLABSI rates and healthcare costs, with infection reductions up to 89% and savings exceeding US$1 million per hospital. Methodological heterogeneity and adherence variability were identified limitations. Conclusion: Structured bundle and checklist implementation reduces CLABSI and healthcare costs, improving patient safety and hospital resource management.
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