Keywords
Physical activity
Risk factors
Postmenopause
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Abstract
Objective: To investigate the association between lifetime physical activity levels in domestic, occupational, and recreational domains and breast cancer risk among users of a public health service. Methods: This observational, quantitative, case-control study was conducted at the Mastology outpatient clinic of Hospital São Paulo, Federal University of São Paulo, between May 2016 and October 2018. A total of 241 women participated, including 80 women with a history of breast cancer and 161 women with benign breast diseases. Physical activity was assessed using the Lifetime Total Physical Activity Questionnaire and the Baecke questionnaire. Analyses included Student's t-test, chi-square test, and multiple logistic regression adjusted for age, ethnicity, and family history. Results: No significant association was found between total lifetime physical activity and breast cancer risk. After stratification by menopausal status, higher occupational physical activity was associated with lower breast cancer odds in postmenopausal women (p=0.03; OR=0.99; 95% CI: 0.98–0.99). Conclusion: Occupational physical activity was associated with lower breast cancer odds in postmenopausal women; however, the results should be interpreted with caution.
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