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Main approaches to normal pregnancy with trophoblastic disease: an integrative literature review
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Keywords

Gestational trophoblastic disease
Twin pregnancy
Hydatidiform mole

How to Cite

Main approaches to normal pregnancy with trophoblastic disease: an integrative literature review. (2020). Electronic Journal Collection Health, 12(3), e3087. https://doi.org/10.25248/reas.e3087.2020

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Abstract

Objective: To describe situations of normal pregnancy with a single or twin fetus and coexisting gestational trophoblastic disease (GDT). Methods: The work was based on a bibliographic review, based on useful scientific articles relevant to the proposed theme. To locate the publications, the electronic databases used were: SCIELO and PUBMED, the search descriptors were: gestational trophoblastic disease, twin pregnancy, hydatidiform mole (MH). For the selection of articles, inclusion and exclusion criteria were used. Results: Studies already concluded on gestational trophoblastic disease, resulted in the investigation being crucial for correct treatment, in addition to using physical examination and clinical history for a better diagnosis. Ultrasonography (US) and human chorionic gonadotropin (β-hCG) must be ordered in all cases, the treatment of DTG is done with vacuum-aspiration. Final considerations: In all available literature on gestation with normal fetus and DTG recommends genetic analysis of the fetal karyotype, to identify triploid fetuses associated with partial spring malformations that evolve with death or diploid fetuses associated with full spring that are generally healthy and they present as normal pregnancies with complete spring type GDT, which can evolve with a viable birth despite the possible maternal complications that may or may not happen.

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