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Insulin resistance and increased cardiovascular risk: a narrative review
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Keywords

Cardiovascular risk
Insulin resistance
Heart failure

How to Cite

Insulin resistance and increased cardiovascular risk: a narrative review. (2020). Electronic Journal Collection Health, 12(9), e3956. https://doi.org/10.25248/reas.e3956.2020

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Abstract

Objective: Conduct a literature review in order to analyze the cardiovascular impacto of insulin resistance. Literature Review: A bibliographic survey from 1979 to 2020 was conducted in the Pubmed database. Twenty scientific literature review articles were selected in which IR appears as a complementary and independent risk factor for the development of cardiovascular abnormalities.It was observed that the main vascular alterations result from the relationship between IR and endothelial, inflammatory and hydroelectrolytic dysfunctions, which culminate primarily in systemic arterial hypertension (SAH). Regarding the cardiac effect, a relationship was observed between IR and changes in contractility and cardiomyocyte metabolism, resulting mainly in ejection disorders and Heart Failure (HF). Final considerations: The relationship between IR and CVD proved to be of paramount importance, thus being of interest to clinical practice in the development of therapies and propedeutics that permeate this pathophysiological knowledge.

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