Abstract
Objective: To clarify the clinic of the serotoninergic syndrome and to allow its correct diagnosis, in such a way that its management becomes effective in a timely manner, resulting in a significant prevention of the morbidity and mortality of this syndrome. Literature review: Serotoninergic syndrome is characterized as an adverse drug manifestation caused by increased levels of serotonin in the central and peripheral nervous system. Formulation of diagnosis criteria became more necessary because of the nonspecific manifestations of it, rapid clinical worsening and increased prescription of serotoninergic drugs in recent decades. However medical doctors don’t have enough knowledge about that syndrome, corroborating with the sub notification of it and making this study more relevant. Final considerations: This investigation revealed that one of the challenges with respect to the aforementioned syndrome is to avoid its incorrect diagnosis, therefore, to know the pillars of its clinic, through continuing medical education, as well as the main pharmacological interactions that culminate. in sickness, it is essential to obtain the correct diagnosis and, therefore, to take the recommended therapeutic measures in time, reducing morbidity and mortality.