Abstract
Objective: Review antibiotic therapy for Infectious Endocarditis (IE) according to the main etiological agents. Literature review: All patients should receive antimicrobial therapy that misses the time necessary to eliminate microorganisms in cardiac vegetation. Since most cases of IS are cause by Gram-positive bacteria, Vancomycin is often an empirical choice applicable in acute cases. Final considerations: Despite the studies deal with the pathophysiological mechanisms clearly, IS remains a disease with high morbidity and mortality and there are far-reaching effects on the quality of life of survivors. Understanding the determining factors for the etiology and evolution of the disease, based on epidemiological data, can contribute significantly to the development of prevention strategies and to follow the treatment with the correct drug. This study can contribute to the education process of health professionals working in this area, as well as improving the formation of a consistent database on the topic.