Abstract
Objective: To analyze the evidence found in scientific publications on the association between bacterial communities and the risk of Colorectal Cancer (CCR). Methods: This is a systematic review of the literatureusing randomized or nonrandomized clinical trials obtained from the PubMed and EMBASE databases that addressed the topic of intestinal microbiota and colorectal cancer in adults and the elderly, published between 2015 and 2020. Results: Identified whereas Bifidobacterias spp and Lactobacillus spp act to reduce the risk of colon cancer, Fusobacteria nucleatum could be used as a marker for the detection of CCR and Eubacterium, Roseburia and Fusobacterium nucleatum have a carcinogenic effect in the colorectal region. Final Considerations: It was analyzed that a group of bacteria is consistently associated with colorectal cancer, highlighting promising biomarkers for the early and non-invasive detection of colorectal neoplasia, making it possible to start treatment in early stages, decreasing morbidity and mortality. In addition to the identification of bacterial colonies capable of reducing the risk of colon cancer, improving treatment and recovery in the postoperative period.