Abstract
Objective: Report the manifestations of Kaposi's Sarcoma in patients with Human Immunodeficiency Virus in order to contribute with theoretical knowledge on the topic. Details of the Case: Kaposi's Sarcoma (SK) is still a common malignancy among patients with Acquired Immunodeficiency Syndrome, it is a rare neoplasm of the lymphatic and blood vessels, which commonly involves the skin. Most gastrointestinal manifestations are associated with skin lesions, when isolated or asymptomatic, it is difficult to confirm the diagnosis, which makes endoscopy with biopsy essential for the diagnosis. The patient in question was undergoing irregular treatment with antiretrovirals, with a CD4 count of 21 cells / mcl, high viral load and gastrointestinal symptoms. Upper gastrointestinal endoscopy was performed with gastric biopsy, showing positive SK immunohistochemistry results, with expression for CD31 and HHV-8. Final Considerations: It is concluded that due to the difficult diagnosis, this report aims at the importance of investigating gastrointestinal complaints in a patient with HIV / AIDS, contributing to a greater knowledge about KS manifestations in these patients.