Abstract
Objective: To investigate the mechanism and effectiveness of immunotherapy in patients infected with COVID-19. Literature review: Inflammation for cytokines are directly associated with the development of COVID-19 and its severity, due to the cytokine storm, immunological pulmonary injury and systemic damage. When infected, the patient develops an inflammatory chain that results in a large quantity of pro-inflammatory cytokines, the cytokine storm, leading to fast development of the disease. The status of hyperinflammation and inflammatory biomarkers are essential tools to this disease prognosis. These biomarkers, complete blood count, CRP, Dimer and image test are important for diagnosis and prognosis for COVID-19 patients, which when detected and regulated early, minimize the risks of worsening the case. Final considerations: Therefore, immune suppression and anti-inflammatory drugs are eligible treatments for the cytokine storm, significantly reducing severe cases. In this way, immunomodulators that block interleukin 6 have potential to inhibit in a specific way the hyperinflammation status.