Abstract
Objective: To search for evidence in the scientific literature regarding the main guidelines and monitoring of drug-resistant tuberculosis patients in primary health care. Methods: Integrative literature review with search in the MEDLINE / PubMed, CINAHL, LILACS and Scopus databases, from which nine scientific articles were selected, included in this research. Results: All articles presented guidelines and monitoring of the treatment of drug-resistant tuberculosis patients. Of these, five highlighted the importance of adherence and strengthening the therapeutic regime. As a follow-up, the articles highlighted the treatment directly observed, the participation of a counselor, the active tracking of patients and their home contacts. Final considerations: The research showed effective guidance and monitoring for drug-resistant tuberculosis cases in primary health care, reinforcing the importance of teamwork, including psychological, social and nutritional support for treatment adherence and prevention of transmission of resistant strains in the community.