Abstract
Objective: Analyze scientific productions on the effectiveness of Janus-Kinase (iJAK) enzyme inhibitors in the treatment of Alopecia Areata. Methods: An integrative review of articles published from 2015 to 2020, in English, Portuguese and Spanish, was carried out. The literature was searched through the Virtual Health Library databases and Pubmed, using the combination of the descriptors "Alopecia areata" and "treatment". Results: From the analysis of publications and considering pre-established inclusion criteria, twenty-one articles were selected from a total of one thousand four hundred and fifty-eight publications. Final Considerations: In view of the results, the iJAK are favorable drugs and of growing importance in the arsenal of the dermatologist in the treatment of Alopecia Areata. Their side effects, when present, were transitory and without great morbidity. However, prospective and comparative studies are necessary to confirm the efficacy and long-term safety of these drugs in the treatment of Alopecia Areata.