Abstract
Objective: The study aimed to analyze the frequency of adverse events resulting from the use of drug therapy in a maternal and child hospital in the State of Pará. Method: A quantitative cross-sectional descriptive study based on the analysis of retrospective data comprising all notifications by active search or voluntary notification received at the hospital pharmacovigilance service for events related to the use of the 24-month drug included in the period between January 1, 2015 as of December 31, 2016s:. Results: The notifications of adverse events, resulting from the use of drug therapy totaled 1,690 records, of which 621 reports refer to the pharmacovigilance service and 1,069 notifications from the pharmaceutical care service. The medical clinic sector had the highest rate, with 44 (51.75%) events in 2015 and 335 (6249%) in 2016. Of the 85 notifications made at the pharmacovigilance service in 2015, in 22 (25.88%), there were interventions, in 63 (74.12%) did not occur to the intervention. In 2016 of the 536 notifications, 280 (52.24%) did not have an intervention record and in 256 (47.76%) a record of interventions was observed. Conclusion: The study allowed the identification of adverse events and their risk factors, showing that the co-responsibility of professionals in the drug system process should be emphasized within the process of permanent education in order to reduce their incidence contributing to the safety of patients in the hospital.