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The impact of dysbiosis on breast cancer progression
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Keywords

Gui bacteria
Breast cancer
Dysbiosis

How to Cite

The impact of dysbiosis on breast cancer progression. (2021). Electronic Journal Collection Health, 13(3), e6645. https://doi.org/10.25248/reas.e6645.2021

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Abstract

Objective: To evaluate and review the immune correlation of dysbiosis in the progression of breast cancer (CM). Bibliographic review: The bacterial flora contributes positively to the body's nutritional, immunomodulatory and metabolic functions, however it has a balance that, if interrupted, can result in systemic consequences, including pro-carcinogenic effects. There is a proven relationship between the intestinal microbiome in balance and the maintenance of the health of the host, not only through local interactions, but through systemic metabolic alterations, with the production of metabolites involved in oncogenesis or tumor suppression, and through the modulation of the immune system and inflammatory processes. The results suggest a link between dysbiosis and CM, which may influence diagnostic and therapeutic implications. Final considerations: In this way, dysbiosis present in different tissues is likely to affect other organs, and each profile can affect the immune system distinctly - either by exacerbating it, or by suppressing it. However, studies with a greater focus on research on the dysbiosis profile of each patient are still needed, to later reconsider the analysis on the staging of CM. In addition, there is an association between the alteration of the microbiota specific to breast tissue and the risk of developing CM, although the mechanism is not known for certain.

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