Abstract
Objective: To elucidate diagnostic and therapeutic aspects about Primary Biliary Cholangitis (PBC), a rare and progressive disease that requires early identification in order to avoid complications. Details of the case: Female patient, 55 years old, sought care for changes in liver enzymes. Denied Pruritus, asthenia and insomnia. Normal physical examination. Requested laboratory tests: TGO 83 U / L; TGP 118 U / L; FA 277 U / L; GGT 310 U / L; AMA 1:40; Negative ANTILKM; Negative AAML; FAN 1: 160. Hepatic biopsy: focal and discrete portal infiltrate, moderate sinusoidal lymphoplasmacytic infiltrate in septal bile ducts with inflammatory cells. Treatment for PBC) was performed with ursodeoxycholic acid 15 mg / kg. Patient returns asymptomatic and with improvement of the laboratory tests. Final considerations: Primary Biliary Cholangitis is characterized by a variety of symptoms, which makes it difficult to diagnose early and start treatment. Thus, it is necessary to know more about the disease by the medical community, in order to prevent its progression and complications.