Google Scholar | Citations: 16429| h-index: 32 | i10-index: 482
Non-alcoholic fatty liver disease: progression and risk of liver cirrhosis development
PDF (Portuguese (Brazil))

Supplementary Files

Certificado de publicação (Portuguese (Brazil))

Keywords

Adult
Liver cirrhosis
Non-alcoholic fatty liver disease

How to Cite

Non-alcoholic fatty liver disease: progression and risk of liver cirrhosis development. (2021). Electronic Journal Collection Health, 13(5), e7036. https://doi.org/10.25248/reas.e7036.2021

Copyright © | All rights reserved.

The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.

Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.

Total reproduction
It is expressly prohibited and must be authorized by the journal.

Abstract

Objective: To relate non-alcoholic fatty liver disease (NGAHD) and the risk of cirrhosis, and to renew and describe the scientific knowledge on the subject over the past five years. Bibliographic review: NASH is defined by the abnormal accumulation of fat in hepatocytes. It is considered a public health problem due to its high prevalence and possible progression to cirrhosis and/or hepatocellular carcinoma. Risk factors are differentiated into modifiable and non-modifiable, with obesity as the underlying disease for the development of NASH. They present various stages of progression, which include hepatic steatosis, Non-Alcoholic Steatohepatitis (NHEA), hepatic fibrosis, cirrhosis and hepatocellular carcinoma. NASHD presents associations with other comorbidities such as metabolic syndrome, type 2 diabetes mellitus (DMT2) and atherogenic dyslipidemia. Final considerations: NASH consists of the accumulation of fat in the hepatocytes of individuals who do not consume or consume less than 30g of alcohol per day, leading to a metabolic disorder, progressive and generally asymptomatic, resulting in late diagnosis and increasing the risk of developing cirrhosis and/or hepatocellular carcinoma.

PDF (Portuguese (Brazil))