Abstract
Objective: Analyze the recent scientific production on tissue necrosis after the application of hyaluronic acid, exploring the epidemiology, pathogenesis, prevention and treatment of this complication. Bibliographic review: It was found that the occurrence of complications after the application of hyaluronic acid is not frequent and most adverse events are mild and self-limiting. Although rare, tissue necrosis triggered by filling with hyaluronic acid is serious and important, however, the evidence is very scarce regarding the ideal treatment. In order not to trigger the worsening of the problem, from the first signs and symptoms (pain, whitening of the skin or changes in color in the distribution of the regional blood vessel), immediately stop the application and inject hyaluronidase as early as possible, combined with warm compresses and local massage, to try to increase blood flow and dissolve the plunger. Final considerations: In the present study, it is possible to observe the importance of deep knowledge of the vascular anatomy of the face, as well as the adequate training of doctors who use injectable fillers, as this procedure has become increasingly common in dermatology offices.