Abstract
Objective: Discuss the relationship between the use of beta-blockers and the exacerbation of Chronic Obstructive Pulmonary Disease (COPD). Methods: This is an Integrative Review carried out in the Scielo, Lilacs and Pubmed databases. The chosen descriptors were “beta blockers”, “Chronic Obstructive Pulmonary Disease” and “exacerbation”, together with the Boolean operators “AND”. After analyzing and applying the inclusion and exclusion methods, twelve articles were selected for data collection. Results: Of the twelve articles analyzed, none article reported that there was an increase in the rate of exacerbations of COPD in patients who used these drugs. Seven articles showed in their results that patients with COPD who used these drugs were less likely to have exacerbations. In addition, some of the selected articles show that selective beta-blockers have better results in these patients. Final Considerations: The use of cardioselective beta-blockers can be maintained in patients with COPD who have a well-established indication for their use, since there is no evidence that they increase the rates of exacerbation and hospitalization in these patients.