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General aspects of Sars-CoV-2 in female reproductive health: a narrative review
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Keywords

Sars-Cov-2
Female fertility
Assisted reproduction

How to Cite

General aspects of Sars-CoV-2 in female reproductive health: a narrative review. (2021). Electronic Journal Collection Health, 13(7), e8019. https://doi.org/10.25248/reas.e8019.2021

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Abstract

Objective: Assess the overall impacts of SARS-CoV-2 infection on female reproductive health as well as on assisted reproduction procedures. Bibliographic review: SARS-CoV-2 appeared in December 2019 and spread rapidly around the world. The virus enters the target cell by binding to the angiotensin converting enzyme (ACE) 2, transmembrane serine protease 2 (TMPRSS2) and 4 (TMPRSS4) and Basigin transmembrane protein (BSG) in host cells, these being present in the cells of the female reproductive system which may significantly impact the reproductive performance of patients affected by SARS-CoV-2. Human reproduction societies have come together to provide recommendations in order to reduce the risk of infection among patients and health professionals during procedures at Embryology clinics, with strict biosafety protocols. Final considerations: The research of women affected by SARS-CoV-2 becomes very important, once the virus can impact in the female reproductive system, being able to infect the ovary, stroma, corpus luteum, uterus, germ cells and oocytes, by the expression of ACE2, TMPRSS2 and BSG.

PDF (Portuguese (Brazil))