Abstract
Objective: Perform acute non-clinical toxicological tests of the juice, jelly and yogurt of the Pilosocereus gounellei. Methods: The study was carried out with 36 female Wistar rats, divided into 3 treated groups and 3 controls, who received 2000mg / kg, orally, of each substance. They were observed for 14 days, with respect to water consumption, food and weight evolution. Subsequently, the animals were euthanized and autopsied. Hematological and biochemical parameters were evaluated, anatomopathological examination was performed. Results: All animals showed weight loss, but there was no change in feed intake. In juice and jelly’s groups, there was a decrease in water consumption. In the juice group there was a decrease in urea, lipase and an increase in chlorine and magnesium. In the jelly group, there was an increase in alanine aminotransferase and mean corpuscular volume. In those who received the yogurt there was a decrease in phosphorus and magnesium, hematocrit and lymphocytes. All of these changes were statistically significant, despite the values being within the normal range, except for ALT. Conclusion: It is concluded that the juice and yogurt of P. gounellei jelly are of low toxicity. Regarding P. gounellei jelly, further studies are needed to rule out hepatotoxicity.