Abstract
Objective: To describe immune-mediated hematological disorders secondary to SARS-CoV-2 infection, exploring both pathophysiological aspects and treatment proposals. Bibliographic review: The infection by SARS-CoV-2 is related to several disorders of the hematological system, whether triggered by the activation of autoimmunity (activation of the complement system, activation of cellular immune responses) or by the direct effect of the virus on the endothelium; they may be related to changes in inflammatory markers or coagulation, which can be considered in the diagnostic search for such manifestations, in addition to prothrombotic states and local or systemic organic involvement. Among the main manifestations described are: Evans Syndrome, Autoimmune Hemolytic Anemia, Antiphospholipid Antibody Syndrome, Immunological purpura and the increase in the neutrophil/lymphocyte ratio. Final considerations: Considering the relevance of COVID-19 as an international health challenge, as well as the lack of specific therapy, it is extremely important to know about the various comorbidities that can be associated, especially to thromboembolic phenomena, due to its expressive morbidity and mortality and possibility of prevention.