Resumen
Objective: To identify challenges and perspectives for the safe administration of medications by Nursing. Methods: This is a descriptive study, consolidated in the integrative review of an exploratory nature. The search for the studies was carried out in the Scientific Eletronic Library Online (SciELO) virtual library in the Latin American and Caribbean Literature in Health Sciences (LILACS) and CAPES Periodicals databases. Results: We found 367 articles relevant to the theme, and after inclusion and exclusion criteria, we selected 10 articles to build this study. Two topics emerged in the discussion: challenges and perspectives on the safe administration of drugs by Nursing. Final considerations: Nursing professionals face challenges such as work overload, failures associated with physical and material structure, environmental conditions (disorganization), and frequent disruptions in being responsible for many procedures and patients. Training and training can be viable strategies to change this problematic scenario, stimulating the Nursing professional to perform good practices in drug administration.