Resumen
Objetivo: Cuantificar la actividad tejido adipose pardo (TAM) mediante imágenes termográficas mediante la acción del chile termogénico y el protocolo de frío en individuos obesos. Métodos: Nueve voluntarios obesos sometidos al protocolo de activación de TAM por frío y por el uso de capsinoides, en un estudio doble ciego. El primer día se realizó una toma de imágenes basales y luego se sometieron al protocolo de frío y posteriormente al protocolo termogénico doble ciego, con intervención de la cápsula. La recolección de imágenes se llevó a cabo durante 2h30. El segundo día, las imágenes se registraron después de la intervención de la cápsula durante 2h30, como se describe el primer día. Las imágenes se analizaron promediando los valores de la escala de grises para verificar una alteración significativa. Resultados: No hubo activación de TAM para el protocolo de frío y placebo y hubo activación de TAM para el protocolo de capsinoides. Discusión: La activación de TAM estuvo relacionada con los tipos de receptores termosensoriales que son diferentes para frío y capsinoides y que están influenciados por el ciclo circadiano, factores ambientales y cantidad de tejido adiposo blanco. Conclusión: Este estudio demostró la correlación entre hábitos y composición corporal en la activación de TAM en la obesidad.
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