Palabras clave
Estomaterapia
Heridas y Lesiones
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Resumen
Objetivo: Analizar las evidencias científicas sobre las estrategias de ingeniería de tejidos con células madre para la cicatrización de heridas crónicas. Métodos: Se trata de una revisión integrativa, realizada en las bases de datos EMBASE, PubMed, Scopus y Web of Science, utilizando los siguientes descriptores: “mesenchymal stem cells”, “adult stem cells”, “embryonic stem cells”, “erythroid precursor cells”, “stem cell therapies”, “chronic wounds” y “wounds and injuries”. Se incluyeron estudios publicados entre 2018 y 2023 que exploraban terapias con células madre, ya sea como tratamiento principal o coadyuvante en pacientes humanos. Resultados: Siete artículos compusieron la muestra final de este estudio, con mayor frecuencia de ensayos clínicos aleatorizados (n: 02). Los resultados indican que las terapias con células madre, especialmente las derivadas del tejido adiposo, desempeñan un papel significativo en la cicatrización de heridas crónicas. Estos enfoques no solo aceleran la regeneración de la piel, sino que también muestran una notable seguridad, evidenciada por la ausencia de efectos secundarios o complicaciones significativas. Consideraciones finales: Los estudios en esta revisión integrativa destacan el potencial de la ingeniería de tejidos con células madre para la cicatrización de heridas crónicas. A pesar de los resultados prometedores, persisten desafíos en la estandarización y la investigación, y las futuras investigaciones son esenciales para consolidar estas estrategias.
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