Resumen
Objetivo: Evaluar las implicaciones clínicas del uso de inhibidores de SGLT2 en el tratamiento de la insuficiencia cardíaca. Métodos: Se realizó una Revisión Integrativa utilizando la plataforma de base de datos PubMed, con el objetivo de localizar fuentes relevantes. La búsqueda se realizó utilizando los términos MeSH "Sodium-Glucose Transporter 2 Inhibitors", "Heart Failure", en asociación con el uso del término booleano "AND" para la búsqueda de artículos, dando como resultado 985 artículos iniciales. Dentro de estos números, debido a los criterios de inclusión y exclusión, sólo 21 fueron seleccionados para análisis. Resultados: El uso de fármacos inhibidores de SGLT2, tienen un alto nivel de seguridad y tolerabilidad en pacientes con IC y han demostrado prevenir los deterioros clínicos inherentes al cuadro clínico de un paciente con IC, así como promover mejores resultados cardiovasculares independientemente del estado diabético, reducir la muerte por todas las causas, reducir la primera hospitalización por IC, así como los resultados renales adversos. Consideraciones finales: Los inhibidores de SGLT2 son beneficiosos en pacientes con insuficiencia cardiaca y fracción de eyección reducida, incluso en ausencia de diabetes. Por lo tanto, las directrices los recomiendan como terapia adicional a los tratamientos estándar para la insuficiencia cardíaca.
Referencias
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