Resumen
Objetivo: Realizar una búsqueda en la literatura para comprender mejor el papel de los tocoferoles y tocotrienoles en la lucha contra el cáncer. Métodos: Esta es una revisión integrativa que utiliza los términos "vitamina E" y "cáncer de seno" y "estrógeno" y "estrés oxidativo" considerando los artículos publicados en los últimos 10 años; Se utilizó el método de diagrama de flujo PRISMA para preparar el artículo. Resultados: Se encontraron once estudios que cubren aspectos in vitro, donde los investigadores utilizaron varios tipos y líneas celulares; in vivo, cuyos animales seleccionados variaron de raza, edad y sexo; y clínica, donde el objeto de estudio fueron mujeres adultas de diferentes grupos de edad. Consideraciones finales: Existe un optimismo cauteloso con respecto al uso de derivados de la vitamina E. Los TT han demostrado una mayor efectividad en el control de los mecanismos en el tratamiento del cáncer de mama. Los estudios también informan una disminución en las complicaciones asociadas, como un aumento de la inmunidad, lo que previene la aparición de otras patologías.
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