Palabras clave
Disbiosis
Insuficiencia Renal Crónica
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Resumen
Objetivo: Evaluar la relación entre los cambios en el microbioma intestinal y la progresión de la enfermedad renal crónica (ERC), así como las complicaciones asociadas y las posibles intervenciones terapéuticas dirigidas al microbioma intestinal que podrían ser eficaces. Métodos: Se trata de una Revisión Integrativa, realizada utilizando la plataforma de base de datos PubMed con el fin de localizar fuentes relevantes para el estudio. La búsqueda se realizó utilizando la estrategia de búsqueda (("Gastrointestinal Microbiome"[MeSH]) OR (Gut Microbiome)) AND ("Renal Insufficiency, Chronic"[MeSH]) para encontrar los artículos, dando como resultado 309 artículos iniciales. De éstos, debido a los criterios de inclusión y exclusión, 20 se convirtieron en fuentes oficiales. Resultados: Los estudios indican que existe una estrecha relación entre la microbiota intestinal y la progresión de la Insuficiencia Renal Crónica, en la que la modulación del eje intestino-riñón es una potencial diana terapéutica. Consideraciones finales: La relación entre la microbiota intestinal y la ERC es clara, pero se necesitan más investigaciones para aclarar y confirmar las hipótesis.
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