Palabras clave
Antimicrobianos
Dosis diaria definida
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Resumen
Objetivo: Describir y comparar el perfil de uso de antimicrobianos durante las dos olas de COVID-19 en un hospital público ubicado en la ciudad de Manaus, Amazonas. Métodos: Se trata de un estudio descriptivo y retrospectivo realizado en un hospital universitario de Manaus, donde se recolectaron datos de historias clínicas, recetas y formularios de solicitud de uso de antimicrobianos. El uso de antimicrobianos se midió según la metodología Anatómico Terapéutico Químico/Dosis Diaria Definida (ATC/DDD). Resultados: Durante el período de la primera ola, el antimicrobiano más consumido fue la ceftriaxona (DDD 1352,01), seguido de piperacilina-tazobactam (DDD 1245,56), cefepima (DDD 1191,23) y meropenem (DDD 1139,88). En la segunda ola, el antimicrobiano más consumido siguió siendo la ceftriaxona con un consumo aún mayor (DDD 2010.55), seguido del meropenem (DDD 1592.22), vancomicina (DDD 722.72) y piperacilina-tazobactam (DDD 704.82). Conclusión: La pandemia de COVID-19 ha impactado el consumo de diferentes clases de antimicrobianos, con notable énfasis en las cefalosporinas y los betalactámicos de amplio espectro. Estos hallazgos resaltan la importancia vital de una vigilancia cuidadosa y un seguimiento constante del consumo de antimicrobianos durante períodos de crisis sanitaria, como la resultante de la pandemia de COVID-19.
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