Palabras clave
Candidemia
Neonatos
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Resumen
Objetivo: Analizar la incidencia y perfil de susceptibilidad antifúngica de Candida. especies aislados de recién nacidos ingresados en maternidades de São Luís-MA. Métodos: Estudio observacional, analítico, transversal, retrospectivo, realizado mediante la recolección de datos de antifungigrama de recién nacidos con diagnóstico de candidiasis o candidemia ingresados desde enero de 2015 a diciembre de 2021. Resultados: Se observaron 237 casos de infección por Candida spp., siendo 55,27% femenino y 44,73%. % masculino. La mayor incidencia se presentó en el grupo de edad de 12 a 14 días y las principales especies aisladas fueron C. albicans, C. parapsilosis y C. tropicalis. La mayor diversidad de Candida patógena se encontró en la sangre y la orina media (p<0,0001), recuperadas de neonatos hospitalizados en la UCI neonatal y en el centro quirúrgico (p<0,0001). Las especies C. albicans, C. duobushaemulonii, C. guillermondii, C. haemulonii, C. parapsilosis, C. krusei mostraron resistencia a 2-3 antifúngicos, entre ellos anfotericina B, caspofungina, fluconazol, 5-fluorocitosina y voriconazol. Conclusión: Los datos alertan sobre la necesidad de implementar medidas de control más estrictas por parte de los Comités de Control de Infecciones Hospitalarias de las maternidades públicas del Estado de Maranhão, para prevenir la propagación de levaduras multirresistentes entre los recién nacidos.
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