Palabras clave
Actividad Antimicrobiana
Biomateriales
Cómo citar
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Resumen
Objetivo: Identificar en la literatura científica pruebas biológicas, in vitro, sobre la acción antimicrobiana del ácido ferúlico (FA). Métodos: El presente estudio es una revisión integradora de la literatura, especialmente en la base de datos PUBMED. Se decidió realizar un estudio en los últimos 5 años debido a las actualizaciones en el tema tratado. Resultados: Se identificaron en las bases de datos un total de 682, conformando una muestra final de 09 obras para la construcción de este artículo. Actualmente, la investigación en el campo del desarrollo de nuevos antimicrobianos con FA se centra en el área de los biomateriales. Se sabe que el biomaterial que más se ha utilizado en estudios es el quitosano. En esta revisión, el 66,6% de los artículos seleccionados incluyeron el uso de biopelículas y conjugados de FA y quitosano. Los análisis microbiológicos incluyeron pruebas de concentración mínima inhibitoria y pruebas bactericidas mínimas. Se pudo verificar que la FA, cuando se asocia con quitosano, presenta mejor acción contra las cepas microbianas probadas. Consideraciones finales: Los FA combinados con quitosano mostraron perspectivas potenciales de aplicación. Sin embargo, se necesita más investigación multidisciplinaria para el desarrollo de antimicrobianos y antibacterianos, que actualmente representan una amenaza creciente para la salud mundial.
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