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Palabras clave
Virus del papiloma humano
Predominio
Tipos de VPH
Cómo citar
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Resumen
Objetivo: Estimar la prevalencia y distribución genotípica del Virus del Papiloma Humano (VPH) en el cáncer de pene en Brasil. Métodos: se trata de una revisión sistemática y metanálisis de estúdios, publicado entre 2000 y 2021, que investigaron la prevalencia y distribución genotípica del VPH en el cáncer de pene en regiones de Brasil, utilizando métodos moleculares. La revisión fue registrada en el International Prospective Register of Systematic Reviews (PROSPERO), realizadas de acuerdo con el informe Preferred Reporting of Systematic Reviews (PRISMA) y la calidad de los estudios incluidos fue evaluada por la Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Studies Reporting Prevalence Data. Resultados: Se incluyeron 15 estudios, totalizando 1.250 casos. La prevalencia combinada del VPH en el cáncer de pene fue del 52,0% y la mayor prevalencia se observó en la región Nordeste (79%), seguida de la región Norte (54%), Sudeste (44%) y Centro-Oeste (31%). El VPH16 fue el genotipo más prevalentes, seguido del VPH6, VPH11, VPH18, VPH51, VPH59, VPH74, VPH31, VPH35 y VPH68. Consideraciones finales: Nuestros resultados confirman la asociación del VPH con el cáncer de pene y resaltan la presencia de genotipos virales no cubiertos por la vacuna profiláctica tetravalente, distribuida por el sistema de salud público de Brasil.
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