Resumen
Objetivo: Describir de manera exhaustiva las principales evidencias clínicas relacionadas con el orden de discontinuación de los vasopresores noradrenalina y vasopresina en pacientes en recuperación de choque séptico. Métodos: Revisión Integrativa de la Literatura. La búsqueda de los estudios se llevó a cabo en las bases de datos LILACS y PubMed. La búsqueda se realizó utilizando las palabras clave registradas en DeCs y MeSH de la siguiente manera: “Choque séptico”, “Vasopresina”, “Hipotensión”, “Agentes vasoconstrictores” y “Norepinefrina”. Resultados: De los nueve artículos analizados, cuatro demostraron una mayor incidencia de hipotensión con la discontinuación de vasopresina antes que norepinefrina en pacientes con choque séptico, tres de ellos en la primera hora después del destete. Estos hallazgos resaltan la necesidad de individualizar el enfoque de discontinuación de vasopresores, considerando la condición hemodinámica de cada paciente y el monitoreo continuo. Consideraciones finales: En pacientes críticos que utilizan vasopresina y norepinefrina de manera concomitante, la interrupción de la norepinefrina antes que la vasopresina promueve una menor incidencia de hipotensión.
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