Resumen
Objetivo: Reportar y sustentar científicamente dos casos de enfermedad de Parkinson durante COVID prolongado tratados en una clínica ambulatoria en condiciones post-COVID. Detalles del caso: Caso 1: Mujer de 41 años, quien luego de 2 años de COVID-19 leve, fue diagnosticada con síntomas extrapiramidales persistentes como bradicinesia y temblores de extremidades en reposo. Caso 2: Hombre de 58 años, hipertenso, diabético, con antecedentes de Síndrome Respiratorio Agudo Severo (SARS) por COVID-19, a quien al cabo de 1 año se le diagnosticó bradicinesia, rigidez, temblores en reposo y periodos de congelamiento. Ambos casos tuvieron un diagnóstico confirmado mediante un ensayo de reacción en cadena de la polimerasa con transcripción inversa (RT-PCR) en tiempo real utilizando un hisopo nasofaríngeo, imágenes por resonancia magnética craneal y una mejoría sustancial de los síntomas con la terapia dopaminérgica. Consideraciones finales: El COVID prolongado es una condición con un amplio espectro de manifestaciones persistentes relacionadas con la infección por COVID-19, incluidas las neuropsiquiátricas. Presentamos dos casos de pacientes con diagnóstico probable de enfermedad de Parkinson desarrollada tras la infección por COVID-19. Hay pocos informes en la literatura. Es importante difundir científicamente dichos hallazgos para el diagnóstico y tratamiento temprano.
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