Resumen
Objetivo: La Enfermedad de Crohn (EC) es una inflamación crónica del tracto gastrointestinal que puede requerir cirugía en casos graves. Este estudio busca comprender los desafíos en el tratamiento de emergencias abdominales en estos pacientes, analizando los efectos de la cirugía en los resultados clínicos y la calidad de vida. Métodos: Se realizó una revisión bibliográfica integradora usando la base de datos PubMed Central, con 21 artículos seleccionados. Resultados: El diagnóstico tardío de la EC aumenta el riesgo de hospitalizaciones y cirugía, dificultando el manejo. Alteraciones como la mioesteatosis están asociadas con peor recuperación postoperatoria, mientras que el papel de la sarcopenia es incierto. Los métodos clínicos y de imagen son cruciales en el tratamiento, especialmente en casos de estenosis y fístulas. Aunque las anastomosis primarias aumentan las complicaciones, las estrategias por etapas reducen las recurrencias. La excisión mesentérica ampliada no incrementa la morbilidad. Las cirugías de emergencia, comunes en la enfermedad penetrante, aumentan el riesgo de complicaciones, requiriendo atención individualizada. Consideraciones finales: El manejo quirúrgico de emergencias abdominales en la EC es desafiante y requiere un enfoque multidisciplinario. El diagnóstico temprano, la evaluación nutricional y el uso de modelos predictivos son esenciales para optimizar los resultados.
Referencias
ABDULKARIM S, et al. Extended versus limited mesenteric excision for operative Crohn's disease: 30-Day outcomes from the ACS-NSQIP database. Int J Colorectal Dis., 2023; 38(1): 268.
BARKAI O, et al. Characterization of risk factors affecting the recurrence of perianal abscesses and complications. The Israel Medical Association Journal: IMAJ, 2024; 26(7): 428-433.
BARREIRO-DE ACOSTA M, et al. Epidemiological, clinical, patient-reported and economic burden of inflammatory bowel disease (ulcerative colitis and Crohn's disease) in Spain: a systematic review. Adv Ther., 2023; 40(5): 1975-2014.
BUNCE JA, et al. Urgency adjusted outcomes of emergency abdominal surgery for inflammatory bowel disease. World Journal of Surgery, 2024; 48(8): 1883-1891.
CAIAZZO A, et al. Increased postoperative use of computed tomography following emergency surgery for ileocaecal Crohn disease. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, 2020; 30(3): 214-217.
CELENTANO V, et al. High complication rate in Crohn's disease surgery following percutaneous drainage of intra-abdominal abscess: a multicentre study. International Journal of Colorectal Disease, 2022; 37(6): 1421-1428.
CELENTANO V, et al. The INTESTINE study: Intended Temporary Stomas in Crohn’s Disease. Protocol for an international multicentre study. Updates in Surgery, 2022; 74: 1691-1696.
CHIARELLO MM, et al. Therapeutic strategies in Crohn's disease in an emergency surgical setting. World Journal of Gastroenterology, 2022; 28(18): 1902-1921.
CONNELLY TM, et al. What is the real morbidity after emergency colectomy for Crohn's disease? A propensity score matched study. Tech Coloproctol., 2023; 27(4): 309-315.
DONNELLY M, et al. Obesity, sarcopenia and myosteatosis: Impact on clinical outcomes in the operative management of Crohn's disease. Inflammatory Bowel Diseases, 2024; 30(9): 1517-1528.
DUAN W, et al. Value of the Prognostic Nutritional Index in surgery for Crohn disease in China and the effects on outcome: A retrospective study. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques, 2023; 33(3): 291-296.
HORENBLAS J, et al. The risk of stroke after prenatal exposure to famine. Journal of Developmental Origins of Health and Disease, 2017; 8(6): 658-664.
IGLESIAS B, et al. Resultados quirúrgicos a corto y mediano plazo por enfermedad de Crohn ileocecal. Revista Medica de Chile, 2022; 150(10): 1310-1316.
KODIA K, et al. Outcomes among malnourished patients with Crohn's disease undergoing elective ileocecectomy: A nationwide analysis. The American Surgeon, 2024; 90(4): 739-747.
KOOMSON D, et al. Making the cut? Reviewing the quality of surgical care in adults with Crohn's disease. British Journal of Hospital Medicine, 2024; 85(6): 1-4.
LAW CC, et al. Risk of postoperative infectious complications from medical therapies in inflammatory bowel disease. The Cochrane Database of Systematic Reviews, 2020; 10(10): CD013256.
LIU RQ, et al. Comparison of primary anastomosis and staged surgery in emergency treatment of complicated Crohn's disease. J Dig Dis., 2020; 21(12): 724-734.
LIU W, et al. Temporal trends in surgery for Crohn's disease: a ten-year single-center retrospective study. International Journal of Colorectal Disease, 2023; 38(1): 221.
LOWE SC, et al. A clinical and radiographic model to predict surgery for acute small bowel obstruction in Crohn’s disease. Abdom Radiol (NY), 2020; 45(9): 2663-2668.
LUDWIG C, et al. Clinical and surgical factors for successful stoma reversal in patients with Crohn's disease-results of a retrospective cohort study. Int J Colorectal Dis., 2022; 37(10): 2237-2244. Erratum in: Int J Colorectal Dis., 2024; 39(1): 24.
NARDONE OM, et al. Impact of sarcopenia on clinical outcomes in a cohort of Caucasian active Crohn's disease patients undergoing multidetector CT-enterography. Nutrients, 2022; 14(17): 3460.
SCHINEIS C, et al. Microscopic inflammation in ileocecal specimen does not correspond to a higher anastomotic leakage rate after ileocecal resection in Crohn's disease. PLoS One, 2021; 16(3): e0247796.
TAJRA JBM, et al. Assessment of risk factors for surgery treatment of Crohn’s disease: A hospital cohort. ABCD Arq Bras Cir Dig, 2023; 36: e1730.
THIN LWY, et al. Ileocolonic end-to-end anastomoses in Crohn's disease increase the risk of early post-operative endoscopic recurrence in those undergoing an emergency resection. Journal of Gastrointestinal Surgery, 2021; 25(1): 241-251.
VERDALLE-CAZES M, et al. Abdominopelvic CT-scan in emergency departments for patients with suspected complications of Crohn’s disease: a single tertiary center experience. BMC Emergency Medicine, 2021; 21: 113.
VERMA A, et al. A simple emergency department based score predicts complex hospitalization in patients with inflammatory bowel disease. Digestive Diseases and Sciences, 2022; 67(2): 629-638.
WALKER GJ, et al. Quality improvement project identifies factors associated with delay in IBD diagnosis. Alimentary Pharmacology & Therapeutics, 2020; 52: 471-480.
WU E, et al. Patients with Crohn's disease undergoing abdominal surgery: Clinical and prognostic evaluation based on a single-center cohort in China. World J Surg., 2022; 46(2): 450-460.
ZABOT GP, et al. Surgical management of adult Crohn's disease and ulcerative colitis patients: A consensus from the Brazilian organization of Crohn's disease and colitis (GEDIIB). Arquivos de Gastroenterologia, 2023; 59(suppl 1): 1-19.
