Palabras clave
Ataxia espinocerebelosa
Temblor distónico
Distonía
Temblor
Cómo citar
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Resumen
Objetivo: Recopilar la evidencia científica disponible sobre la ataxia en pacientes con temblor distónico. Métodos: Se trata de una revisión integrativa. Se utilizaron las siguientes bases de datos: Medline (vía PubMed), Embase y Web of Science. Además, se realizó una búsqueda secundaria en la lista de referencias de los estudios incluidos y en la literatura gris. Los criterios de elegibilidad fueron artículos que describieran pacientes diagnosticados con temblor distónico y ataxia. Resultados: Se identificaron 105 estudios, de los cuales 18 fueron incluidos. Doce de los estudios son reportes de casos y seis son series de casos, con una muestra total de 27 pacientes. El temblor distónico en los miembros superiores estuvo presente en casi el 80% de los pacientes, seguido del temblor distónico de la cabeza (33,3%) y el temblor distónico del cuello y los miembros inferiores (14,8%). Se han identificado varios tipos de ataxias. Consideraciones finales: La ataxia cerebelosa es una condición neurológica con heterogeneidad clínica que puede identificarse concomitantemente con temblor distónico. El temblor distónico puede ser el síntoma de presentación inicial. Varios genes son responsables de la ataxia; Sin embargo, se necesitan estudios observacionales adicionales para establecer una asociación entre la ataxia y el temblor distónico.
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