Resumen
Objetivo: Identificar predictores de mortalidad en adultos mayores con fracturas de fémur proximal sometidos a cirugía dentro de un año. Método: Estudio con 142 pacientes ≥60 años, ingresados en un hospital de referencia para trauma ortopédico en la principal macrorregión de cobertura. Se utilizaron análisis univariados (chi-cuadrado, regresión de Cox) y métodos de Kaplan-Meier, Log-Rank, Breslow y Tarone-Ware. Resultados: La mortalidad fue del 30,5%, prevalente en mujeres (23,4%), con comorbilidades (28,1%), fractura trocantérea (16,3%), lado izquierdo afectado (17,7%) y uso de clavo intramedular (16,3%). Hubo mayor mortalidad entre pacientes con ASA I/II (28,4%), hemoglobina <12 g/dL (21%), sin transfusión sanguínea (23,4%), INR >1 (19%), estancia hospitalaria <7 días (22,7%), ingreso en UCI (20,6%) y sin entrenamiento de la marcha (23,4%). El análisis de Cox indicó edad >85 años (HR=3,31; p=0,034), ingreso en UCI (HR=2,54; p=0,009) y falta de entrenamiento de la marcha (HR=4,12; p<0,0001) como factores significativamente asociados con la mortalidad. Conclusión: La edad avanzada, el ingreso en UCI y la falta de entrenamiento de la marcha antes del alta hospitalaria son predictores de muerte dentro del año posterior a la cirugía de fractura de fémur proximal en ancianos.
Referencias
ALSHEIKH KA, et al. One-year postoperative mortality rate among the elderly with hip fractures at a single tertiary care center. Annals of Saudi medicine, 2020; 40(4): 298-304, 2020.
ANTUNES J, et al. Fatores preditivos de morte após cirurgia para tratamento de fratura proximal do fêmur. Revista Brasileira de Ortopedia, 2019; 54: 402-407.
ATZMON R, et al. The effect of postoperative weight-bearing status on mortality rate following proximal femoral fractures surgery. Archives of Orthopaedic and Trauma Surgery, 2022; 1-7.
BELMONT PJ, et al. Risk factors for complications and in-hospital mortality following hip fractures: a study using the National Trauma Data Bank. Archives of orthopaedic and trauma surgery, 2014; 134: 597-604.
BIÇEN Ç, et al. Analysis of risk factors affecting mortality in elderly patients operated on for hip fractures: A retrospective comparative study. Acta Orthop Traumatol Turc, 2021; 55(6): 493-499.
CHA Y, et al. Effect of heart failure on postoperative short and long-term mortality in elderly patients with hip fracture. Injury, 2020; 51(3): 694-698.
DAUGAARD CL, et al. Is mortality after hip fracture associated with surgical delay or admission during weekends and public holidays? A retrospective study of 38,020 patients. Acta orthopaedica, 2012; 83(6): 609-613.
DEMIREL E e ŞAHIN A, Predictive value of blood parameters and comorbidities on three-month mortality in elderly patients with hip fracture. Cureus, 2021; 13(10).
DOWNEY C, et al. Changing trends in the mortality rate at 1-year post hip fracture-a systematic review. World journal of orthopedics, 2019; 10(3): 166.
DUBLJANIN-RASPOPOVIC E, et al. Does early functional outcome predict 1-year mortality in elderly patients with hip fracture?. Clinical Orthopaedics and Related Research®, 2013; 471(8): 2703-2710.
ESPINOSA KA, et al. Pre-operative factors associated with increased mortality in elderly patients with a hip fracture: a cohort study in a developing country. Injury, 2018; 49(6): 1162-1168.
GALBRAITH AS, et al., Diabetes mellitus and gender have a negative impact on the outcome of hip fracture surgery—a pilot study. Journal of Orthopaedic Research®, 2020; 38(4): 834-842.
GUERRA MTE, et al. One-year mortality of elderly patients with hip fracture surgically treated at a hospital in Southern Brazil. Revista Brasileira de Ortopedia, 2017; 52: 17-23.
HOLVIK K, et al. Predictors of mortality in older hip fracture inpatients admitted to an orthogeriatric unit in Oslo, Norway. Journal of aging and health, 2010; 22(8): 1114-1131.
INSTITUTO BRASILEIRO DE GEOGRAFIA E ESTATÍSTICA (IBGE). Pesquisa Nacional por Amostra de Domicílios. (Pnad Contínua), 2022. Rio de Janeiro.
KLESTIL T, et al. Impact of timing of surgery in elderly hip fracture patients: a systematic review and meta-analysis. Scientific reports, 2018; 8(1): 13933.
MENÉNDEZ-COLINO R, et al. Baseline and pre-operative 1-year mortality risk factors in a cohort of 509 hip fracture patients consecutively admitted to a co-managed orthogeriatric unit (FONDA Cohort). Injury, 2018; 49(3): 656-661.
MORAES C, et al. Tools and scores for general and cardiovascular perioperative risk assessment: a narrative review. Revista do Colégio Brasileiro de Cirurgiões, 2022; 49: e20223124.
MORRI M, et al. One-year mortality after hip fracture surgery and prognostic factors: a prospective cohort study. Scientific reports, 2019; 9(1): 18718.
OMSLAND TK, et al. Mortality following the first hip fracture in Norwegian women and men (1999–2008). A NOREPOS study. Bone, 2014; 63: 81-86.
PEREIRA SRM et al. The impact of prefracture and hip fracture characteristics on mortality in older persons in Brazil. Clinical Orthopaedics and Related Research®, 2010; 468: 1869-1883.
PETROS RSB, et al. Influência das fraturas do fêmur proximal na autonomia e mortalidade dos pacientes idosos submetidos a osteossíntese com haste cefalomedular. Revista Brasileira de Ortopedia, 2017; 52: 57-62.
SILVA JCA, et al. Fraturas de fêmur em idosos nas diferentes regiões do Brasil de 2015 a 2020: análise dos custos, tempo de internação e total de óbitos. Revista Pesquisa em Fisioterapia, 2021; 11(4): 798-806.
TURGUT N, et al. Standard and Newly Defined Prognostic Factors Affecting Early Mortality after Hip Fractures. Cureus, 2022; 14(1).
VON FRIESENDORFF M, et al. Hip fracture, mortality risk, and cause of death over two decades. Osteoporosis International, 2016; 27: 2945-2953.
WANG C, et al. Excess mortality after hip fracture among the elderly in Taiwan: a nationwide population-based cohort study. Bone, 2103; 56(1): 147-153.
XING F, et al. The risk-adjusted Charlson comorbidity index as a new predictor of one-year mortality rate in elderly Chinese patients who underwent hip fracture surgery. Orthopaedics & Traumatology: Surgery & Research, 2021; 107(3): 102860.
XU BY, et al. Predictors of poor functional outcomes and mortality in patients with hip fracture: a systematic review. BMC musculoskeletal disorders, 2019; 20(1): 1-9.
YOMBI JC, et al. Low haemoglobin at admission is associated with mortality after hip fractures in elderly patients. The bone & joint journal, 2019; 101(9): 1122-1128.
