Keywords
Pregnancy
Prematurity
How to Cite
Copyright © | All rights reserved.
The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.
Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.
Total reproduction
It is expressly prohibited and must be authorized by the journal.
Abstract
Objective: The objective of this study is to carry out a detailed analysis of data related to premature births in pregnant women diagnosed with COVID-19 during the pandemic period, in addition to investigating the clinical repercussions of the disease for both the mother and the fetus. Methods: This is an integrative review with a time frame from 2019 to 2024 in databases such as PubMed and the Google Scholar search engine, referring to pregnancy and covid-19. Results: Most of the studies analyzed in this review point to specific clinical characteristics and both maternal and fetal outcomes in pregnant women who contracted COVID-19. Studies highlight that infected pregnant women may often have no symptoms or only mild symptoms, which highlights the importance of active screening for this group of patients. Regarding obstetric results, there was no clear association between the type of delivery and the transmission of the disease to the newborn, while some studies indicate a possible correlation between COVID-19 and premature birth. Final considerations: COVID-19 presents unique challenges for pregnant women, with significant impacts on maternal and newborn health.
References
BLITZ MJ, et al. Intensive care unit admissions for pregnant and nonpregnant women with coronavirus disease 2019. American Journal of Obstetrics & Gynecology, 2020.
BOAVENTURA MD, et al. Covid-19 na gravidez, parto e pós-parto imediato: implicações e intercorrências/ Covid-19 in Pregnancy, Childbirth and the Immediate Postpartum Period: Implications and complications. Brazilian Journal of Development, 7(7): 73368–73382.
BRASIL. Pré-Natal no SUS. 2024. Disponível em: https ://www.gov.br/secom/pt-br/acesso-a-informacao/comunicabr/lista-dos-programas/pre-natal-no-sus. Acessado em: 15/05/2024.
BRITO JG, et al. Características clínicas, sociodemográficas e desfechos de gestantes hospitalizadas com COVID-19. Research, Society and Development, 10(17): 33101723049.
CAO D, et al. Clinical analysis of ten pregnant women with COVID-19 in Wuhan, China: A retrospective study. International Journal of Infectious Diseases, 2020; 95: 294–300.
CARBONE L, et al. COVID-19 vaccine and pregnancy outcomes: A systematic review and meta-analysis. Int J Gynaecol Obstet. 2022; 159(3): 651-661.
CHEN H, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. 2020; 395(10229): 1038.
CHEN S, et al. Clinical analysis of pregnant women with 2019 novel coronavirus pneumonia. J Med Virol. 2020; 92(9): 1556-1561.
CORDES AK e HEIM A. Rapid random-access detection of the novel SARS-coronavirus-2 (SARS-CoV 2, previously 2019-nCoV) using an open access protocol for the Panther Fusion. J Clin Virol, 2020; 125: 104305.
DIRIBA K, et al. The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal-fetal transmission: a systematic review and meta-analysis. Eur J Med Res. 2020; 25(1): 39.
FEBRASGO. COVID-19 e Gestação: Perguntas e Respostas. 2020. Disponível em: https ://www.febrasgo.org.br/images/SOGIMIG-COVID19.pdf. Acessado em: 15/05/2024.
FERRAZZI E, et al. Vaginal delivery in SARS-CoV-2-infected pregnant women in Northern Italy: a retrospective analysis. BJOG. 2020; 127(9): 1116-1121.
GONG X, et al. CT characteristics and diagnostic value of COVID-19 in pregnancy. PLoS ONE, 2020: 15(7): 235134.
HANTOUSHZADEH S, et al. Maternal death due to COVID-19. Am J Obstet Gynecol. 2020; 223(1):109- 12.
JUNIOR GA, et al. COVID-19 e sua relação com a gravidez e neonatos: uma revisão sistemática. Rev. Bras. Saúde Mater. Infant., Recife, 2021; 21(3): 729-759.
KAYEM G, et al. A snapshot of the Covid-19 pandemic among pregnant women in France. J Gynecol Obstet Hum Reprod. 2020; 49(7): 101826.
KUMAR D, et al. COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacy. Transl Res. 2023; 251: 84-95.
LIU D, et al. Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis [published correction appears in AJR Am J Roentgenol. AJR Am J Roentgenol. 2020; 215(1): 127-132.
MCPHAIL A, et al. Gestational Weight Gain During the COVID-19 Pandemic. Matern Child Health J. 2023; 27(9): 1454-1459.
MINGUITO AU, et al. The Effect of Online Supervised Exercise throughout Pregnancy on the Prevention of Gestational Diabetes in Healthy Pregnant Women during COVID-19 Pandemic: A Randomized Clinical Trial. Int J Environ Res Public Health. 2022; 19(21): 14104.
NOGUEIRA CK, et al. Análise nacional do perfil das gestantes acometidas pela COVID-19. Braz. J. Hea. Rev, Curitiba, 3(5): 14267-14278.
ONCEL MY, et al. A multicenter study on epidemiological and clinical characteristics of 125 newborns born to women infected with COVID-19 by Turkish Neonatal Society [published correction appears in Eur J Pediatr. Eur J Pediatr. 2021; 180(3): 733-742.
PAHO. Histórico da pandemia de COVID-19. Organização Mundial da Saúde, 2020. Disponível em < https ://www.paho.org/pt/covid19/historico-da-pandemia-covid-19>.
PEREZ MO, et al. Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain. JAMA. 2020; 324(3): 296-299.
PINHO MD, et al. Assistência à gestante durante a pandemia da Covid-19: complicações na gestação / Assistance to pregnant women during the Covid-19 pandemic: complications in pregnancy. Brazilian Journal of Development, 7(12), 110998–111013.
QIANCHENG X, et al. Coronavirus disease 2019 in pregnancy. Int J Infect Dis. 2020; 95: 376-383.
SCHWARTZ DA. An Analysis of 38 Pregnant Women with COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes. Arch Pathol Lab Med, 2020.
SOCIEDADE BRASILEIRA DE INFECTOLOGIA. Informativo da sociedade brasileira de infectologia: primeiro caso confirmado de doença pelo novo coronavírus (covid-19) no brasil – 26/02/2020. São Paulo – SP.
WU Y, et al. The outbreak of COVID-19: An overview. Journal of the Chinese Medical Association, 2020; 83(3): 217-220.
WU YT, et al. Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China. PLoS Med. 2020;17(7): 1003195.
YANG H, et al. Clinical features and outcomes of pregnant women suspected of coronavirus disease 2019. J Infect. 2020; 81(1): 40-44.
ZHANG L, et al. Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) infection during late pregnancy: a report of 18 patients from Wuhan, China. BMC Pregnancy Childbirth. 2020; 20(1): 394.
ZHU NA, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med, 2020; 382(8): 727–33.