Keywords
Pregnant women
Prenatal care
Vertical transmission of infectious diseases
How to Cite
Copyright © | All rights reserved.
The journal holds the exclusive copyright for the publication of this article under the terms of Brazilian law 9610/98.
Partial reproduction
The use of parts of the texts, figures and questionnaire of the article is free, being mandatory the citation of the authors and journal.
Total reproduction
It is expressly prohibited and must be authorized by the journal.
Abstract
Objective: To evaluate new cases of congenital syphilis (CS) and the determining aspects for its incidence in the city of Passo Fundo, RS, between 2015 and 2019. Methods: This is a cross-sectional observational study and data collection was performed on the platform DATASUS. Results: During this period, 739 pregnant women were diagnosed with syphilis and 413 newborns were diagnosed with CS. The highest prevalence of infection was in women aged between 20 and 29 years. In 49% of cases the diagnosis was made in the third trimester of pregnancy; in 43% of the cases the stage of the maternal disease was ignored and for 74% of them the prescribed treatment was penicillin. Regarding the cases of CS, 86% of the mothers underwent prenatal care and 45% of them had the treatment considered inadequate; 29% of pregnant women did not undergo treatment. Conclusion: The incidence of CS in the period was higher than that recommended by the Pan American Health Organization, highlighting the need to improve prenatal care and early diagnosis.
References
ALVES PIC, et al. Temporal evolution and characterization of congenital syphilis cases in Minas Gerais, Brazil, 2007-2015. Revista Ciência e Saúde Coletiva, 2020; 25(8): 2949–2960.
ANDRADE ALMB, et al. Diagnóstico tardio de Sífilis Congênita: Uma realidade na atenção à saúde da mulher e da criança no Brasil. Revista Paulista de Pediatria, 2018; 36(3): 376–381.
ARAÚJO CL, et al. Incidência da sífilis congênita no Brasil e sua relação com a Estratégia Saúde da Família. Revista Saúde Pública, 2012; 46(3): 479-48.
ARAÚJO EC, et al. Evaluation of prenatal care for syphilis and HIV detection in pregnant women at-tended in a rural area of Pará State, Brazil. Revista Pan-Amazônica de Saúde, 2018; 9(1): 1.
ARAÚJO MAL, et al. Factors associated with unfavorable outcomes caused by Syphilis infection in pregnancy. Revista Brasileira de Saúde Materno Infantil, 2019; 19(2): 411–4.
AVELLEIRA JCR e BOTIINO G. Syphilis: Diagnosis, treatment and control. Anais Brasileiros de Derma-tologia, 2006; 81(2): 111–126.
BEZERRA MLMB, et al. Congenital syphilis as a measure of maternal and child healthcare, Brazil. Emerging Infectious Diseases, 2019; 25(8): 1469–147.
BRASIL. MINISTÉRIO DA SAÚDE. Boletim Epidemiológico de Sífilis 2019. Disponível em: https ://www.gov.br/aids/pt-br/central-de-conteudo/boletins-epidemiologicos/2019/sifilis/boletim_sifilis_2019_internet-1.pdf/view. Acessado em: 06 de maio de 2021.
BRASIL. MINISTÉRIO DA SAÚDE. Diretrizes para o Controle da Sífilis Congênita. 2005. Disponível em: https ://bvsms.saude.gov.br/bvs/publicacoes/diretrizes_controle_sifilis_congenita.pdf. Acessado em: 06 de maio de 2021.
BRASIL. MINISTÉRIO DA SAÚDE. Diretrizes para o Controle da Sífilis Congênita: manual de bolso. 2006. Disponível em: https ://bvsms.saude.gov.br/bvs/publicacoes/manual_sifilis_bolso.pdf. Acessado em: 06 de maio de 2021.
BRASIL. MINISTÉRIO DA SAÚDE. Sífilis: Estratégias para Diagnóstico no Brasil. 2010. Disponível em: https ://bvsms.saude.gov.br/bvs/publicacoes/sifilis_estrategia_diagnostico_brasil.pdf. Acessado em: 06 de maio de 2021.
BROOKS GF, et al. Microbiologia médica de Jawetz, Melnick e Adelberg. Porto Alegre: AMGH, 2014; 26.
BROWN DL e FRANK JE. Diagnosis and management of syphilis. American Family Physician, 2003; 68(2): 283-290.
COELHO JMR, et al. Sífilis: um panorama epidemiológico do Brasil e do município de Volta Redon-da/RJ. Brazilian Journal of Health Review, 2018; 1(1): 128–147.
COOPER JM e SÁNCHEZ PJ. Congenital syphilis. Seminars in Perinatology, 2018; 42(3): 176–184.
DOMINGUES RMSM, et al. Sífilis congênita: evento sentinela da qualidade da assistência pré-natal. Revista de Saúde Pública, 2013; 47(1): 147–157.
GONG T, et al. Treatment evaluation to improve preventing mother to child transmission among women with syphilis. Scientific Reports, 2019; 9: 1–5.
MAGALHÃES DMS, et al. A sífilis na gestação e sua influência na morbimortalidade materno-infantil. Comunicação em Ciências da Saúde, 2011; 22(1): 43–54.
MILLER R e KARRAS DJ. Congenital syphilis - United States 2003-2008. Annals of Emergency Medici-ne, 2010; 56(3): 295–296.
PAHO - Pan American Health Organization. Elimination of mother-to-child transmission of hiv and syphilis in the Americas: update 2016. Disponível em: https : //iris.paho.org/bitstream/handle/10665.2/34072/9789275119556eng.pdf?sequence=4&isAllowed=y. Acessado em: 06 de junho de 2021.
PAHO - Pan American Health Organization. New generations free of HIV, syphilis, hepatitis B and Cha-gas disease in the Americas 2018. Disponível em: https ://iris.paho.org/bitstream/handle/10665.2/50993/9789275120675_eng.pdf. Acessado em: 06 de ju-nho de 2021.
PIRES ACS, et al. Ocorrência de sífilis congênita e os principais fatores relacionados aos índices de transmissão da doença no Brasil da atualidade – revisão de literatura. Revista Uningá, 2014; 19(1): 58–64.
QIN J, et al. Reported Estimates of Adverse Pregnancy Outcomes among Women with and without Syphilis: A Systematic Review and Meta-Analysis. PLoS One, 2014; 9(7): 1–16.
RADOLF JD, et al. Treponema pallidum, the syphilis spirochete: Making a living as a stealth pathogen. Nature Reviews Microbiology, 2016; 14(12): 744–759.
RIO GRANDE DO SUL. Secretaria de Estado da Saúde. Departamento de Ações em Saúde. Coorde-nação Estadual de IST/Aids. Boletim Epidemiológico: HIV/Aids e Síflis. Porto Alegre: ESP/RS; 2020. Disponível em: https ://saude.rs.gov.br/upload/arquivos/202303/31173118-boletim-epidemiologico-hiv-aids-e-sifilis-2020.pdf. Acessado em: 06 de junho de 2021.
ROCHA AFB, et al. Complicações, manifestações clínicas da sífilis congênita e aspectos relacionados à prevenção: revisão integrativa. Revista Brasileira de Enfermagem, 2021; 74(4): 1–9.
WATSON-JONES D, et al. Syphilis in pregnancy in Tanzania. II. The effectiveness of antenatal syphilis screening and single dose benzathine penicillin treatment for the prevention of adverse pregnancy out-comes. The Journal of Infectious Diseases, 2002; 186(7): 948–957.