Abstract
Objective: To report a clinical case regarding the non-surgical endodontic treatment of two teeth with apical periodontitis, associated with clinical and radiographic follow-up demonstrating rapid regression of the periapical pathology. Case details: A 35-year-old female patient reported pain while eating. Clinical examination revealed extensive carious lesions on teeth 11 and 12. Radiographically, a well-defined radiolucent area was observed in the apical region, suggestive of a periapical lesion (Ørstavik PAI: score 4) associated with the aforementioned teeth. Based on clinical tests and radiographic findings, a diagnosis of symptomatic apical periodontitis in tooth 11 and asymptomatic apical periodontitis in tooth 12 of pulpal necrotic origin was established. The treatment consisted of necropulpectomy using the Crown-Down technique, with 2.5% sodium hypochlorite irrigation and intracanal medication with HPG paste for one week. Root canal obturation was performed using the active lateral condensation technique associated with Sealer 26® cement. Final consideration: Clinical and radiographic follow-up was performed every three months over one year, showing an effective approach with no pain symptoms and rapid reduction of the periapical bone rarefaction (PAI score: 1).
References
AAE Consensus Conference Recommended Diagnostic Terminology. J Endod. 2009;35(12):1634.
AHMAD MZ, et al. Calcium hydroxide as an intracanal medication for postoperative pain during primary root canal therapy: A systematic review and meta-analysis with trial sequential analysis of randomised controlled trials. J. Evid. Based Dent. Pract. 2021; 22(1): 101680.
AL-HELOU N, et al. Which endodontic access cavity is best? A literature review. Br Dent J. 2023;335–339.
BARUWA AO, et al. Comparative analysis of endodontic 0.15 stainless-steel K-files: exploring design, composition, and mechanical performance. Dentistry J. 2024;12(2):29.
BLASZCZYK-POŚPIECH A, et al. Endodontic sealers and innovations to enhance their properties: a current review. Materials. 2025;18(18):4259. doi:10.3390/ma18184259
BOUTSIOUKIS C, ARIAS-MOLIZ MT. Present status and future directions – irrigants and irrigation methods. Int Endod J 2022;55(Suppl 3):588-612. doi: 10.1111/iej.13739. PMID: 35338652.
BUCCHI C, et al. Non-surgical root canal treatment and retreatment versus apical surgery in treating apical periodontitis: a systematic review. Int Endod J. 2022.
BÜRKLEIN S, ARIAS A. Effectiveness of root canal instrumentation for the treatment of apical periodontitis: a systematic review and meta-analysis. Int Endod J. 2022.
CASTILLO-PÁEZ J, ÁLVAREZ M. Reparação de tecidos perirradiculares em tratamento endodôntico não cirúrgico: uma revisão. Rev Cient Odontol (Lima). 2024;12(3):e210.
COPE AL, et al. Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults. Cochrane Database Syst Rev. 2018;9:CD010645.
DE OLIVEIRA AF, et al. Endodontic treatment in dental element with periapical lesion: literature review. Braz J Dev. 2022;8(1):752–765.
DINIZ E, et al. Apical periodontitis healing and postoperative pain following endodontic treatment with a reciprocating single-file, single-cone approach: a randomized controlled pragmatic clinical trial. PLoS ONE. 2020;15(2):e0227347.
DUNCAN HF, et al. Treatment of pulpal and apical disease: the European Society of Endodontology (ESE) S3-level clinical practice guideline. Int Endod J. 2023;56(S3):238–295.
ELBAHARY S, et al. Effects of different irrigation protocols on dentin surfaces as revealed through quantitative 3D surface texture analysis. Sci Rep. 2020;10:1.
FORTE LR, et al. Main endodontic obturation techniques: a literature review. Rev CPAQV. 2024;16(2):1.
GAVINI G, et al. Nickel–titanium instruments in endodontics: a concise review of the state of the art. Braz Oral Res. 2018;32(suppl 1).
GIOVANNA P, et al. Métodos de agitação das soluções irrigadoras: uma revisão de literatura. RSBO. 2022;19(1):171–183.
GONÇALVES AN, et al. Apical transportation of manual NiTi instruments and a hybrid technique in severely curved simulated canals. J Conserv Dent. 2015;18(6):436.
KARAMIFAR K, et al. Endodontic periapical lesion: an overview on etiology, diagnosis and current treatment modalities. Eur Endod J. 2020;5(2).
KATO AS, et al. Investigation of the efficacy of passive ultrasonic irrigation versus irrigation with reciprocating activation: an environmental scanning electron microscopic study. J Endod. 2016;42(4):659–663.
LOPES HP, SIQUEIRA JF. Endodontia: biologia e técnica. 5ª ed. Rio de Janeiro: Guanabara Koogan; 2020. 832 p.
LOUREIRO C, et al. Quantitative proteomic analysis in symptomatic and asymptomatic apical periodontitis. Int Endod J. 2021;54(6):834–847.
LUISA M, et al. A new approach to endodontic access in anterior teeth – a pilot study. Rev Odontol UNESP. 2023;52.
LUO X, et al. Mechanisms of bone remodeling and therapeutic strategies in chronic apical periodontitis. 2022;12:22 jul.
ØRSTAVIK D, et al. The periapical index: a scoring system for radiographic assessment of apical periodontitis. Dent Traumatol. 1986;2(1):20–34.
PATEL S, et al. Cone beam computed tomography in endodontics – a review of the literature. Int Endod J. 2019;52(8).
RAJASEKHAR R, et al. Volumetric correlation of periapical lesion with Ørstavik’s periapical index: a retrospective cone-beam computed tomographic study. J Conserv Dent Endod. 2024;27(10):1054–1058.
RAZUMOVA S, et al. Evaluation of the efficiency of smear layer removal during endodontic treatment using scanning electron microscopy: an in vitro study. BMC Oral Health. 2025;25(1).
ROLIM LB, et al. Root canal obturation in endodontic treatment success: techniques and considerations – literature review. Rev FT. 2024;28.
SADAF D, AHMAD MZ. Calcium hydroxide (Ca[OH]₂) as an intracanal medication may significantly reduce endotoxins level from infected teeth. J. Evid. Based Dent. Pract. 2021; 21(3): 101616.
SANTOS AF, et al. Análise da resistência compressiva e capacidade de escoamento de diferentes cimentos obturadores endodônticos. Rev Eletr Acervo Saúde. 2024;24(10):e16699.
SIGURDSSON A, et al. Six-month healing success rates after endodontic treatment using the novel GentleWave™ System: the pure prospective multi-center clinical study. J Clin Exp Dent. 2016;8(3):e290–298.
SIQUEIRA JF, et al. Apical root canal microbiome associated with primary and posttreatment apical periodontitis: a systematic review. Int Endod J. 2024.
SIQUEIRA JF, RÔÇAS IN. Clinical implications and microbiology of bacterial persistence after treatment procedures. J Endod. 2008;34(11):1291–1301.
ZOU X, et al. Expert consensus on irrigation and intracanal medication in root canal therapy. Int J Oral Sci. 2024;16(1):1–10.
GLUSKIN AH, et al. Minimally invasive endodontics: challenging prevailing paradigms. Br Dent J. 2014;216(6):347–353.
MOHAMMADI Z, DUMMER PMH. Properties and applications of calcium hydroxide in endodontics and dental traumatology. Int Endod J., 2011;44(8):697–730.
