Abstract
Introduction: Wegener's granulomatosis (GW), also known as granulomatosis with polyangeitis, is a rare and idiopathic autoimmune disease, which is marked by inducing granulomatous inflammation and systemic vasculitis involving vessels of small and medium calibers. The early diagnosis of GW requires a high index of suspicion, due to the low specificity of the initial symptoms. Currently there is a shortage of data related to the profile of patients in the country, with its clinical and epidemiological characteristics. Method: This study was developed using data from the patient during a hospitalization period. Description of the case report: A male patient, 18 years old, was admitted complaining of epistaxis, starting two weeks ago with systemic arterial hypertension (SAH) and oliguria. He evolved with uremic syndrome and laboratory showing azotemia, being indicated emergency dialysis. After investigation, he presented a 1:20 c-ANCA reagent, Wegener's granulomatosis being interrogated for the presence of positive c-ANCA, renal involvement and sinusopathy / epistaxis. He progressed clinically without further complications and was discharged after ambulatory dialysis. Being referred to the rheumatology outpatient clinic. Conclusion: It is necessary to include Wegener's granulomatosis in the etiological investigation of patients with a history of renal insufficiency associated with respiratory tract involvement, given the severity of the disease progression.