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Clinical spectrum of COVID-19 infection in human organisms: narrative review
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Keywords

Coronavirus infections
Signs and symptoms
General symptoms
Symptom exacerbation
Human

How to Cite

Clinical spectrum of COVID-19 infection in human organisms: narrative review. (2020). Electronic Journal Collection Health, 46, e3763. https://doi.org/10.25248/reas.e3763.2020

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Abstract

Objective: To analyze through a review the most relevant clinical presentations of SARS-CoV-2 infection. Bibliographic Review: COVID-19 has a wide spectrum of presentations. The asymptomatic form is a diagnostic challenge, leading to underreporting. They are believed to occur in individuals with efficient antiviral defense and effective immune response, but unable to completely block the virus. Mild Flu Syndrome represents 80% of symptomatic cases, manifested through fever, cough, fatigue, dyspnoea and myalgia. Severe cases, of 5-10% of those symptomatic, are usually expressed by pneumonia, with changes in vital signs, dyspnea or organ dysfunction, in addition, they may progress to an Acute Respiratory Discomfort Syndrome, with respiratory complications, radiographic and PaO2 / FiO2 changes. Sepsis and septic shock by COVID-19 have an even greater chance of an unfavorable outcome, conditions that indicate the patient's stay in an intensive care environment. Final Considerations: Little is known about COVID-19, but its high potential for transmissibility and its variability in clinical presentations are recognized as complicating factors in controlling the epidemic.

PDF (Portuguese (Brazil))