Abstract
Objective: Review how is the behavior of the coinfection Human Immunodeficiency Virus (HIV)/Leishmaniose, as well as clinical features. Bibliographic review: The Leishmaniasis Cutaneous is an endemic disease not contagious, caused by protozoa of the genus Leishmania that affect skin and mucous membranes. The transmission happens through infected insects bite. On the other hand, Acquired Immunodeficiency Syndrome is characterized by the destruction of CD4 lymphocytes, impairing the body's cellular immunity and engendering space for opportunists infections, like Leishmaniasis Cutaneous. Therefore, the clinical manifestation of the coinfection HIV/Leishmaniasis occurs differently than the leishmaniasis manifestation, because there is the appearance of atypical clinical features like the involvement of the gastrointestinal and respiratory tract, in addition to the low CD4 + lymphocyte count. Final considerations: From the studies, it was possible to infer that the coinfection HIV/Leishmaniasis has a big detrimental effect on the immune system, besides presenting difficulties to the treatment difficulties in treatment because there is no effective immune response.