Abstract
Objective: To highlight the main clinical, histological and radiological aspects involved in the differential diagnosis of the main benign liver tumors. Bibliographic review: Despite their benign nature, benign liver tumors can lead to complications and serious outcomes. Despite the fact that this entity is asymptomatic in most cases, it is of utmost importance to perform an appropriate and careful management to reach the differential diagnosis. In general, adenomas can be differentiated from other lesions by appearing in a clinical context of oral contraceptive use and presenting as a solid and well-defined lesion. Focal nodular hyperplasia, on the other hand, is classically characterized by a central scar. The hemangiomas are well delimited, solid, single or multiple, hypervascularized lesions located peripherally. Cysts are evidenced by an anechoic image, with posterior wall reinforcement and spherical or oval shape. Final considerations: The evaluation of liver lesions can be challenging when not seen globally, however the literature shows that when evaluated by the union of clinical, histological, laboratory and imaging findings the peculiarities of each lesion become evident, allowing the correct diagnosis and clinical management.