Resumo
Objetivo: Analisar, à luz da literatura científica, a associação entre o uso de contraceptivos hormonais combinados e o risco de desenvolvimento de tromboembolismo venoso em mulheres, contribuindo para uma compreensão crítica e atualizada dessa relação sob a perspectiva clínica e epidemiológica. Métodos: Trata-se de uma revisão integrativa da literatura, orientada pelas recomendações do checklist PRISMA 2020, com busca nas bases PubMed/MEDLINE, SciELO e Biblioteca Virtual em Saúde. Foram incluídos estudos publicados entre 2021 e 2026, em português ou inglês, disponíveis na íntegra e relacionados ao tema. Resultados: A busca identificou 312 registros, dos quais oito estudos compuseram a síntese final. Os achados evidenciaram aumento do risco tromboembólico, especialmente em formulações contendo etinilestradiol, enquanto contraceptivos com estrogênios naturais apresentaram perfil mais favorável em parte dos estudos. Observou-se também que idade, obesidade, tabagismo, trombofilias e predisposição genética influenciam esse risco. Considerações finais: Há associação entre contraceptivos hormonais combinados e tromboembolismo venoso, embora essa relação varie conforme a formulação e o perfil clínico da usuária, reforçando a necessidade de prescrição individualizada.
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